Key features and details
- Rabbit polyclonal to P70 S6 Kinase beta/SRK
- Suitable for: WB, IP
- Reacts with: Human
- Isotype: IgG
Product nameAnti-P70 S6 Kinase beta/SRK antibody
See all P70 S6 Kinase beta/SRK primary antibodies
DescriptionRabbit polyclonal to P70 S6 Kinase beta/SRK
Tested applicationsSuitable for: WB, IPmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Dog, Chimpanzee, Ferret, Rhesus monkey, Orangutan
Synthetic peptide within Human P70 S6 Kinase beta/SRK aa 430-482 (C terminal). The exact sequence is proprietary.
Database link: NP_003943.2
- HeLa whole cell lysate
Previously labelled as P70 S6 Kinase beta.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab70271 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000 - 1/10000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).|
|IP||Use at 2-6 µg/mg of lysate.|
FunctionPhosphorylates specifically ribosomal protein S6.
Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
- 70 kDa ribosomal protein S6 kinase 2 antibody
- EC 22.214.171.124 antibody
- KS6B2_HUMAN antibody
All lanes : Anti-P70 S6 Kinase beta/SRK antibody (ab70271) at 0.04 µg/ml
Lane 1 : HeLa whole cell lysate at 15 µg
Lane 2 : HeLa whole cell lysate at 5 µg
Predicted band size: 53 kDa
Observed band size: 53 kDa
Additional bands at: 35 kDa, 67 kDa, 69 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 30 seconds
ab70271 has not yet been referenced specifically in any publications.