Recombinant
RabMAb

Recombinant Anti-p75 NGF Receptor antibody [EPR18373-211] (ab222666)

Overview

  • Product name

    Anti-p75 NGF Receptor antibody [EPR18373-211]
    See all p75 NGF Receptor primary antibodies
  • Description

    Rabbit monoclonal [EPR18373-211] to p75 NGF Receptor
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    Anti-p75 NGF Receptor antibody is used in our 90-minute ELISA kit, Mouse p75 NGF Receptor ELISA kit (ab205569), and available in the matched antibody pair kit (ab215075).

Properties

Applications

Our Abpromise guarantee covers the use of ab222666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.

Target

  • Function

    Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
  • Sequence similarities

    Contains 1 death domain.
    Contains 4 TNFR-Cys repeats.
  • Domain

    Death domain is responsible for interaction with RANBP9.
    The extracellular domain is responsible for interaction with NTRK1.
  • Post-translational
    modifications

    N- and O-glycosylated.
    O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
    Phosphorylated on serine residues.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD271 antibody
    • CD271 antigen antibody
    • Gp80 LNGFR antibody
    • Gp80-LNGFR antibody
    • Low affinity nerve growth factor receptor antibody
    • Low affinity neurotrophin receptor p75NTR antibody
    • Low-affinity nerve growth factor receptor antibody
    • Nerve growth factor receptor antibody
    • Nerve growth factor receptor TNFR superfamily member 16 antibody
    • NGF receptor antibody
    • Ngfr antibody
    • p75 ICD antibody
    • p75 Neurotrophin receptor antibody
    • p75 NTR antibody
    • p75(NTR) antibody
    • p75NTR antibody
    • TNFR Superfamily Member 16 antibody
    • TNFRSF16 antibody
    • TNR16_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 16 antibody
    see all

Images

  • Example of mouse p75 NGF Receptor standard curve in 1X Cell Extraction Buffer PTR using recombinant p75 NGF Receptor RabMAb antibody (ab222666) and a recombinant monoclonal antibody. Background-subtracted values (mean +/- SD) are graphed.

    For a matched antibody pair set, see Mouse p75 NGF Receptor Matched Antibody Pair Kit (ab215075).

    For a complete ELISA kit, see Mouse p75 NGF Receptor ELISA kit (ab205569).

References

ab222666 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab222666.
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