APC Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab176522)
Key features and details
- APC Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted
- Suitable for: Flow Cyt
- Reacts with: Rabbit, Cat, Human, Ferret
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
APC Anti-p75 NGF Receptor antibody [NGFR5], prediluted
See all p75 NGF Receptor primary antibodies -
Description
APC Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted -
Host species
Mouse -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Specificity
The epitope is localized within amino acids 1 - 160. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Rabbit, Cat, Human, Ferret
Predicted to work with: Non human primatesDoes not react with: Mouse, Rat -
Immunogen
Full length native protein (purified) corresponding to Human p75 NGF Receptor. Purified CD271 protein isolated from Human melanoma cell line A875.
Database link: P08138 -
Positive control
- Human blood cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.098% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading...
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Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
NGFR5 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
- PE Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab157333)
- Anti-p75 NGF Receptor antibody [NGFR5] - BSA and Azide free (ab212682)
- PE/Cy7® Anti-p75 NGF Receptor antibody [NGFR5] (ab234270)
- PerCP/Cy5.5® Anti-p75 NGF Receptor antibody [NGFR5] (ab234446)
- Anti-p75 NGF Receptor antibody [NGFR5] (ab3125)
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab176522 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
10 μl reagent / 100 μl of whole blood |
Notes |
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Flow Cyt
Use 10µl for 106 cells. 10 μl reagent / 100 μl of whole blood |
Target
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Function
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Domain
Death domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1. -
Post-translational
modificationsN- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 101101519 Cat
- Entrez Gene: 101680416 Ferret
- Entrez Gene: 4804 Human
- Entrez Gene: 100349095 Rabbit
- Omim: 162010 Human
- SwissProt: P08138 Human
- Unigene: 415768 Human
- Unigene: 681726 Human
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Alternative names
- CD271 antibody
- CD271 antigen antibody
- Gp80 LNGFR antibody
see all
Datasheets and documents
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Datasheet download
References (0)
ab176522 has not yet been referenced specifically in any publications.