Anti-p8/NUPR1 antibody (ab6028)
Key features and details
- Rabbit polyclonal to p8/NUPR1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-p8/NUPR1 antibody
See all p8/NUPR1 primary antibodies -
Description
Rabbit polyclonal to p8/NUPR1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human p8/NUPR1 aa 62-82.
Sequence:ERKLVTKLQNSERKKRGARR
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab6028 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 9 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 9 kDa). |
Target
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Function
Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype. -
Tissue specificity
Highly expressed in pancreas. -
Post-translational
modificationsPhosphorylated. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 26471 Human
- SwissProt: O60356 Human
- Unigene: 513463 Human
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Alternative names
- Candidate of metastasis 1 antibody
- COM1 antibody
- Nuclear protein 1 antibody
see all
Datasheets and documents
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Datasheet download
References (5)
ab6028 has been referenced in 5 publications.
- He W et al. NUPR1 is a novel potential biomarker and confers resistance to sorafenib in clear cell renal cell carcinoma by increasing stemness and targeting the PTEN/AKT/mTOR pathway. Aging (Albany NY) 13:14015-14038 (2021). PubMed: 34030133
- Wu B et al. Quercetin induced NUPR1-dependent autophagic cell death by disturbing reactive oxygen species homeostasis in osteosarcoma cells. J Clin Biochem Nutr 67:137-145 (2020). PubMed: 33041510
- Liu Z & Xu L UBE2S promotes the proliferation and survival of human lung adenocarcinoma cells. BMB Rep 51:642-647 (2018). PubMed: 30545437
- Cui Z et al. Nanodiamond autophagy inhibitor allosterically improves the arsenical-based therapy of solid tumors. Nat Commun 9:4347 (2018). PubMed: 30341298
- Palam LR et al. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death Dis 6:e1913 (2015). WB . PubMed: 26469962