Overview

  • Product name

  • Description

    Rabbit polyclonal to PABPC3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 411-609 of Human PABPC3 (Q9H361).

  • Positive control

    • Jurkat, Raji and K562 cell lysates; Human hepatoma tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 70 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.
  • Tissue specificity

    Testis specific.
  • Sequence similarities

    Belongs to the polyadenylate-binding protein type-1 family.
    Contains 1 PABC domain.
    Contains 4 RRM (RNA recognition motif) domains.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • PABP-3 antibody
    • PABP3 antibody
    • PABP3_HUMAN antibody
    • PABPC3 antibody
    • PABPL3 antibody
    • Poly(A) binding protein 3 antibody
    • Poly(A)-binding protein 3 antibody
    • Polyadenylate binding protein 3 antibody
    • Polyadenylate-binding protein 3 antibody
    • RP11-165I9.5 antibody
    • Testis specific poly(A) binding protein antibody
    • Testis-specific poly(A)-binding protein antibody
    • tPABP antibody
    see all

Images

  • ab126178, at 1/500 dilution, staining PABPC3 in paraffin-embedded Hepatoma tissue by Immunohistochemistry.

References

ab126178 has not yet been referenced specifically in any publications.

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