Recombinant Anti-PAC-2 antibody [EPR9947(2)] (ab172909)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9947(2)] to PAC-2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-PAC-2 antibody [EPR9947(2)]
See all PAC-2 primary antibodies -
Description
Rabbit monoclonal [EPR9947(2)] to PAC-2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human PAC-2 aa 100-200. The exact sequence is proprietary.
Database link: Q969U7 -
Positive control
- Caco-2, HepG2, Hela and Jurkat cell lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR9947(2) -
Isotype
IgG
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab172909 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/1000 - 1/5000. Predicted molecular weight: 29 kDa.
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Notes |
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WB
1/1000 - 1/5000. Predicted molecular weight: 29 kDa. |
Target
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Function
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. -
Tissue specificity
Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. -
Sequence similarities
Belongs to the PSMG2 family. -
Post-translational
modificationsDegraded by the proteasome upon completion of 20S proteasome maturation. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 56984 Human
- Entrez Gene: 107047 Mouse
- Entrez Gene: 291539 Rat
- Omim: 609702 Human
- SwissProt: Q969U7 Human
- SwissProt: Q9EST4 Mouse
- Unigene: 464652 Human
- Unigene: 150701 Mouse
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Alternative names
- CD40 ligand activated specific transcript 3 antibody
- CLAST3 antibody
- HCCA3 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab172909 has not yet been referenced specifically in any publications.