Recombinant
RabMAb

Recombinant Anti-PAC-2 antibody [EPR9947(2)] (ab172909)

Overview

  • Product name

    Anti-PAC-2 antibody [EPR9947(2)]
    See all PAC-2 primary antibodies
  • Description

    Rabbit monoclonal [EPR9947(2)] to PAC-2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC/IF or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PAC-2 aa 100-200. The exact sequence is proprietary.
    Database link: Q969U7

  • Positive control

    • Caco-2, HepG2, Hela and Jurkat cell lysates
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR9947(2)
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab172909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 29 kDa.
IHC-P Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IP.
  • Target

    • Function

      Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
    • Tissue specificity

      Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue.
    • Sequence similarities

      Belongs to the PSMG2 family.
    • Post-translational
      modifications

      Degraded by the proteasome upon completion of 20S proteasome maturation.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • CD40 ligand activated specific transcript 3 antibody
      • CLAST3 antibody
      • HCCA3 antibody
      • Hepatocellular carcinoma susceptibility protein antibody
      • Hepatocellular carcinoma-susceptibility protein 3 antibody
      • HSPC260 antibody
      • HsT1707 antibody
      • Likely ortholog of mouse CD40 ligand activated specific transcript 3 antibody
      • MDS003 antibody
      • PAC-2 antibody
      • PAC2 antibody
      • proteasome (prosome, macropain) assembly chaperone 2 antibody
      • Proteasome assembly chaperone 2 antibody
      • psmG2 antibody
      • PSMG2_HUMAN antibody
      • TNFSF5IP1 antibody
      • Tumor necrosis factor superfamily member 5-induced protein 1 antibody
      see all

    Images

    • All lanes : Anti-PAC-2 antibody [EPR9947(2)] (ab172909) at 1/1000 dilution

      Lane 1 : Caco-2 cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : Jurkat cell lysate

      Predicted band size: 29 kDa

    References

    ab172909 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab172909.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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