Anti-PACAP receptor/ADCYAP1R1 antibody (ab183103)
Key features and details
- Rabbit polyclonal to PACAP receptor/ADCYAP1R1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-PACAP receptor/ADCYAP1R1 antibody
See all PACAP receptor/ADCYAP1R1 primary antibodies -
Description
Rabbit polyclonal to PACAP receptor/ADCYAP1R1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide within Human PACAP receptor/ADCYAP1R1 aa 1-100. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: P41586-2 -
Positive control
- Hela cell, mouse stomach tissue and brain tissue lysates; Human tonsil tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
(without Mg2+ and Ca2+) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab183103 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200.
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WB |
1/1000 - 1/5000. Predicted molecular weight: 56 kDa.
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Notes |
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IHC-P
1/50 - 1/200. |
WB
1/1000 - 1/5000. Predicted molecular weight: 56 kDa. |
Target
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Function
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. -
Tissue specificity
Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 117 Human
- Entrez Gene: 11517 Mouse
- Omim: 102981 Human
- SwissProt: P41586 Human
- SwissProt: P70205 Mouse
- Unigene: 377783 Human
- Unigene: 44245 Mouse
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Alternative names
- ADCYAP1 R1 antibody
- ADCYAP1R 1 antibody
- ADCYAP1R1 antibody
see all
Images
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All lanes : Anti-PACAP receptor/ADCYAP1R1 antibody (ab183103) at 1/2000 dilution
Lane 1 : Hela cell lysate
Lane 2 : Mouse stomach tissue lysate
Lane 3 : Mouse brain tissue lysate
Lysates/proteins at 40 µg per lane.
Secondary
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Predicted band size: 56 kDa
Exposure time: 5 minutes10%SDS-PAGE
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Immunohistochemical analysis of paraffin embedded Human tonsil tissue labeling ADCYAP1R1 with ab183103 at 1/70 dilution. Image on the right is treated with the synthetic peptide.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab183103 has not yet been referenced specifically in any publications.