Anti-PACAP receptor/ADCYAP1R1 antibody (ab216664)
Key features and details
- Rabbit polyclonal to PACAP receptor/ADCYAP1R1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-PACAP receptor/ADCYAP1R1 antibody
See all PACAP receptor/ADCYAP1R1 primary antibodies -
Description
Rabbit polyclonal to PACAP receptor/ADCYAP1R1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide aa 269-295 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P41586 -
Positive control
- WB: Rat heart and mouse brain lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab216664 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/100 - 1/1000. Predicted molecular weight: 53 kDa.
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Notes |
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WB
1/100 - 1/1000. Predicted molecular weight: 53 kDa. |
Target
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Function
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. -
Tissue specificity
Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 117 Human
- Entrez Gene: 11517 Mouse
- Entrez Gene: 24167 Rat
- Omim: 102981 Human
- SwissProt: P41586 Human
- SwissProt: P70205 Mouse
- SwissProt: P32215 Rat
- Unigene: 377783 Human
see all -
Alternative names
- ADCYAP1 R1 antibody
- ADCYAP1R 1 antibody
- ADCYAP1R1 antibody
see all
Images
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All lanes : Anti-PACAP receptor/ADCYAP1R1 antibody (ab216664) at 1/200 dilution
Lane 1 : Rat brain lysate
Lane 2 : Rat heart lysate
Secondary
All lanes : Goat anti-rabbit IgG (H+L), HRP-conjugated at 1/3000 dilution
Developed using the ECL technique.
Predicted band size: 53 kDa
Observed band size: 58 kDa why is the actual band size different from the predicted?12% gel
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All lanes : Anti-PACAP receptor/ADCYAP1R1 antibody (ab216664) at 1/300 dilution
Lane 1 : Mouse brain lysate
Lane 2 : A549 cell lysate
Developed using the ECL technique.
Predicted band size: 53 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab216664 has not yet been referenced specifically in any publications.