Key features and details
- Rabbit polyclonal to PACAP receptor/ADCYAP1R1
- Suitable for: IHC-P, ICC, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PACAP receptor/ADCYAP1R1 antibody
See all PACAP receptor/ADCYAP1R1 primary antibodies
DescriptionRabbit polyclonal to PACAP receptor/ADCYAP1R1
Tested applicationsSuitable for: IHC-P, ICC, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
This product was previously labelled as PACAP receptor
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Constituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab28670 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 40-60 kDa (predicted molecular weight: 55 kDa).|
FunctionThis is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
Tissue specificityMost abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family.
Cellular localizationCell membrane.
- Information by UniProt
- ADCYAP1 R1 antibody
- ADCYAP1R 1 antibody
- ADCYAP1R1 antibody
ab28670 has been referenced in 4 publications.
- Frausto RF et al. ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing. PLoS One 14:e0218279 (2019). PubMed: 31194824
- Frederiksen SD et al. Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans. Neuroscience 393:319-332 (2018). PubMed: 30336190
- Rice FL et al. Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine. Cephalalgia 37:1350-1372 (2017). PubMed: 27852962
- Ortner A et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles. J Drug Target 18:457-67 (2010). ICC ; Human . PubMed: 20050817