Overview

  • Product name

    Anti-PACAP receptor/ADCYAP1R1 antibody
    See all PACAP receptor/ADCYAP1R1 primary antibodies
  • Description

    Rabbit polyclonal to PACAP receptor/ADCYAP1R1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Sheep, Cow
  • Immunogen

    Synthetic peptide corresponding to Human PACAP receptor/ADCYAP1R1 aa 50-150 conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab109076)

  • Positive control

    • This antibody gave a positive signal in the following tissue lysates: Human brain; Human liver; Human pancreas; Human small intestine.
  • General notes

     This product was previously labelled as PACAP receptor

     

Properties

Applications

Our Abpromise guarantee covers the use of ab95278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).

Target

  • Function

    This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
  • Tissue specificity

    Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADCYAP1 R1 antibody
    • ADCYAP1R 1 antibody
    • ADCYAP1R1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I antibody
    • PAC 1 antibody
    • PAC1 antibody
    • PAC1R antibody
    • PACAP receptor 1 antibody
    • PACAP type I receptor antibody
    • PACAP-R-1 antibody
    • PACAP-R1 antibody
    • PACAP1 R antibody
    • PACAPR antibody
    • PACAPRI antibody
    • PACR_HUMAN antibody
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop antibody
    • Pituitary adenylate cyclase activating polypeptide receptor antibody
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor antibody
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for antibody
    • Pituitary adenylate cyclase-activating polypeptide type I receptor antibody
    • pvr1 antibody
    see all

Images

  • All lanes : Anti-PACAP receptor/ADCYAP1R1 antibody (ab95278) at 1 µg/ml

    Lane 1 : Human brain tissue lysate - total protein (ab29466)
    Lane 2 : Human small intestine tissue lysate - total protein (ab29276)

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 53 kDa
    Observed band size: 53 kDa
    Additional bands at: 51 kDa (possible cleavage fragment)


    Exposure time: 10 minutes


    The band observed at 51 kDa could potentially be a cleaved form of PACAP receptor/ADCYAP1R1 due to the presence of a 20 amino acid signal peptide. A positive signal was also seen in both Human liver and Human pancreas tissue lysates.

References

ab95278 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab95278.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up