PACAP-Related Peptide (PRP) (human), PAC1, VPAC1 and VPAC2 receptor antagonist (ab142331)

Overview

  • Product name

    PACAP-Related Peptide (PRP) (human), PAC1, VPAC1 and VPAC2 receptor antagonist
  • Description

    PAC1, VPAC1 and VPAC2 receptor antagonist
  • Biological description

    PAC1, VPAC1 and VPAC2 receptor antagonist. Excitatory neuropeptide. Induces Ca2+mobilization. Role in hypertension and stress responses. Active in vivo and in vitro.
  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Basille-Dugay M  et al. Activation of PAC1 Receptors in Rat Cerebellar Granule Cells Stimulates Both Calcium Mobilization from Intracellular Stores and Calcium Influx through N-Type Calcium Channels. Front Endocrinol (Lausanne) 4:56 (2013). Read more (PubMed: 23675369) »
  • Farnham MM  et al. PACAP causes PAC1/VPAC2 receptor mediated hypertension and sympathoexcitation in normal and hypertensive rats. Am J Physiol Heart Circ Physiol 303:H910-7 (2012). Read more (PubMed: 22886412) »
  • Ogi K  et al. Molecular cloning and characterization of cDNA for the precursor of rat pituitary adenylate cyclase activating polypeptide (PACAP). Biochem Biophys Res Commun 173:1271-9 (1990). Read more (PubMed: 2268329) »

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