Anti-PADI4 / PAD4 antibody [OTI4H5] (ab128086)

Mouse monoclonal PADI4 / PAD4 antibody [OTI4H5]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Human. Cited in 16 publication(s). Independently reviewed in 1 review(s).

Publishing research using ab128086? Please let us know so that we can cite the reference in this datasheet.

ab128086 has been referenced in 17 publications.

  • Liu M  et al. PADI4-mediated epithelial-mesenchymal transition in lung cancer cells. Mol Med Rep 19:3087-3094 (2019). PubMed: 30816464
  • Engström M  et al. Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis. J Transl Med 16:214 (2018). PubMed: 30064459
  • Fan T  et al. Hypoxia-induced autophagy is inhibited by PADI4 knockdown, which promotes apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis. Mol Med Rep 17:5116-5124 (2018). PubMed: 29393388
  • McNee G  et al. Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma. Leukemia 31:373-381 (2017). PubMed: 27400413
  • Blachère NE  et al. High-Titer Rheumatoid Arthritis Antibodies Preferentially Bind Fibrinogen Citrullinated by Peptidylarginine Deiminase 4. Arthritis Rheumatol 69:986-995 (2017). PubMed: 28029744
  • Naffah de Souza C  et al. Alkaline pH Promotes NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation: A Matter of Mitochondrial Reactive Oxygen Species Generation and Citrullination and Cleavage of Histone. Front Immunol 8:1849 (2017). PubMed: 29375550
  • Wang W  et al. B-cell specific Moloney leukemia virus insert site 1 and peptidyl arginine deiminase IV positively regulate carcinogenesis and progression of esophageal squamous cell carcinoma. Oncol Lett 13:4349-4356 (2017). PubMed: 28599437
  • Zhou Y  et al. Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils. Front Immunol 8:1200 (2017). PubMed: 28993780
  • Sun B  et al. Citrullination of NF-?B p65 promotes its nuclear localization and TLR-induced expression of IL-1ß and TNFa. Sci Immunol 2:N/A (2017). PubMed: 28783661
  • Katkar GD  et al. NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction. Nat Commun 7:11361 (2016). PubMed: 27093631
  • Ghari F  et al. Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response. Sci Adv 2:e1501257 (2016). PubMed: 26989780
  • Grabcanovic-Musija F  et al. Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation. Respir Res 16:59 (2015). PubMed: 25994149
  • Spengler J  et al. Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid. Arthritis Rheumatol 67:3135-45 (2015). PubMed: 26245941
  • Blachère NE  et al. Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen. Arthritis Res Ther 17:369 (2015). WB ; Human . PubMed: 26684871
  • Savchenko AS  et al. Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development. J Thromb Haemost 12:860-70 (2014). IHC-P ; Human . PubMed: 24674135
  • Kolodziej S  et al. PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation. Nat Commun 5:3995 (2014). WB, ChIP ; Human . PubMed: 24874575
  • Obermayer A  et al. New aspects on the structure of neutrophil extracellular traps from chronic obstructive pulmonary disease and in vitro generation. PLoS One 9:e97784 (2014). ICC/IF ; Human . PubMed: 24831032

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up