Overview

  • Product name

    Paeoniflorin, Adenosine A1 receptor activator
  • Description

    Adenosine A1 receptor activator
  • Biological description

    Adenosine A1 receptor activator with neuroprotective and antidepressant effects. Upregulates serotonergic systems in vivo. Blood brain barrier permeable.
  • Purity

    > 98%
  • CAS Number

    23180-57-6
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    480.46
  • Molecular formula

    C23H28O11
  • PubChem identifier

    442534
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water and ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O
  • Source

    Paeonia lactiflora

  • Research areas

References

This product has been referenced in:

  • Qiu F  et al. The antidepressant-like effects of paeoniflorin in mouse models. Exp Ther Med 5:1113-1116 (2013). Read more (PubMed: 23599734) »
  • Mao QQ  et al. Protective effects of paeoniflorin against corticosterone-induced neurotoxicity in PC12 cells. Phytother Res 26:969-73 (2012). Read more (PubMed: 22131171) »
  • Zhu Y  et al. [Advanced achievements about neuroprotective mechanisms of paeoniflorin]. Zhongguo Zhong Yao Za Zhi 35:1490-3 (2010). Read more (PubMed: 20822028) »
  • Liu Y  et al. [Mechanism of protective effect of pretreatment of paeoniflorin on injured cortical neurons with corticosterone]. Zhongguo Zhong Yao Za Zhi 35:2457-9 (2010). Read more (PubMed: 21141500) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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