Product namePaeonol, anti-inflammatory and antioxidant agent
DescriptionPotent anti-inflammatory and antioxidant agent
Biological descriptionPotent anti-inflammatory and antioxidant agent. Enhances endogenous antioxidant activity. Reduces Bax and Caspase-3 expression. Shows anti-ischemic, renal protective and cardioprotective effects in vivo. Orally active.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 5 mM, in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
This product has been referenced in:
- Lee H et al. Paeonol, a major compound of moutan cortex, attenuates Cisplatin-induced nephrotoxicity in mice. Evid Based Complement Alternat Med 2013:310989 (2013). Read more (PubMed: 24171038) »
- Tseng YT et al. Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons. Shock 37:312-8 (2012). Read more (PubMed: 22089194) »
- Li H et al. Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats. PLoS One 7:e48872 (2012). Read more (PubMed: 23139821) »