Overview

  • Product name
    Anti-PAEP / Glycodelin antibody [13]
    See all PAEP / Glycodelin primary antibodies
  • Description
    Mouse monoclonal [13] to PAEP / Glycodelin
  • Host species
    Mouse
  • Tested applications
    Suitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human PAEP/ Glycodelin.

  • General notes

    Previously labelled as Placental Protein 14 / Glycodelin A. 

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.097% Sodium azide
    Constituents: 0.0268% PBS, 2.9% Sodium chloride
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    13
  • Isotype
    IgG1
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/7000.

Target

  • Function
    This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy.
  • Sequence similarities
    Belongs to the calycin superfamily. Lipocalin family.
  • Post-translational
    modifications
    At least two differentially glycosylated forms are found. Glycodelin-A (GdA) (amniotic fluid) with contraceptive and immunosuppressive activities and glycodelin-S (Gds) (seminal plasma) whose role is not yet known. The gender-specific glycosylation may serve to regulate key process involved in human reproduction.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha uterine protein antibody
    • gD antibody
    • GdA antibody
    • GdF antibody
    • GdS antibody
    • Glycodelin A antibody
    • Glycodelin antibody
    • Glycodelin F antibody
    • Glycodelin S antibody
    • MGC138509 antibody
    • MGC142288 antibody
    • PAEG antibody
    • PAEP antibody
    • PAEP_HUMAN antibody
    • PEG antibody
    • PEP antibody
    • Placental Protein 14 / Glycodelin A antibody
    • Placental protein 14 antibody
    • PP14 antibody
    • Pregnancy-associated endometrial alpha-2 globulin antibody
    • Progestagen-associated endometrial protein antibody
    • Progesterone-associated endometrial protein antibody
    see all

Images

  • ab17247 staining endometrial tissue from the late secretory phase.  Staining is restricted to the glandular cells.

References

This product has been referenced in:
  • Wang Y  et al. Placental protein 14 as a potential biomarker for diagnosis of preterm premature rupture of membranes. Mol Med Rep 18:113-122 (2018). Read more (PubMed: 29749501) »
  • Wang P  et al. The Role of Placental Protein 14 in the Pathogenesis of Endometriosis. Reprod Sci N/A:N/A (2013). IHC ; Human . Read more (PubMed: 23670949) »
See all 5 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Question
Answer

Thank you for contacting us.

Yes, in addition to the primary antibody, only a secondary antibody is needed.

I can recommend a couple secondariesthat are HRP-conjugated:

https://www.abcam.com/Donkey-polyclonal-Secondary-Antibody-to-Mouse-IgG-H-L-HRP-pre-adsorbed-ab7061.html

https://www.abcam.com/Goat-polyclonal-Secondary-Antibody-to-Mouse-IgG-H-L-HRP-pre-adsorbed-ab97040.html


I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Use our products? Submit an Abreview. Earn rewards!
https://www.abcam.com/abreviews

Read More

Answer

Thank you for contacting us.

This antibody ab17247 has so far only been tested in indirect ELISA (coating the sample to the plate, and then using primary and secondary antibodies). It has not been tried in sandwich ELISA, thus, we do not have a specific antibody pair that was tested.

None of the other anti-Placental Protein 14 / Glycodelin A antibodies have been tested for ELISA and human samples, but if the customer would like to try one of these antibodies together with ab17247 in a sandwich ELISA, they can use our testing discount program:

For UNTESTED species and/or applications, we have established a testing discount program. Here is a brief description of how it works:

The testing discount program is for customers who like to use an antibody/protein/kit on an untested species/application. You would purchase the antibody/protein/kit at full price, test it and submit an Abreview with your data (positive or negative). On your next order you will receive a discount for ONE antibody/protein at the full price (100%) of the antibody/protein you have tested, or a full price discount for the amount paid for the kit. The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.
This programapplies to ELISA kits and other kits we offer.


Please let me know if the customer would be interested in this.



I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Use our products? Submit an Abreview. Earn rewards!
https://www.abcam.com/abreviews

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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