Overview

  • Product name

  • Description

    Rabbit polyclonal to PAF-R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human PAF-R (C terminal). The exact sequence is proprietary.
    Database link: P25105

  • Positive control

    • WB: HL-60 membrane extract.
  • General notes

    Previously labelled as PAF Receptor. 

Properties

Applications

Our Abpromise guarantee covers the use of ab226936 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

Target

  • Function

    Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.
  • Tissue specificity

    Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • OTTHUMP00000004041 antibody
    • OTTMUSP00000010350 antibody
    • PAF R antibody
    • PAF receptor antibody
    • PAF-R antibody
    • PAFr antibody
    • Platelet activating factor receptor antibody
    • Platelet-activating factor receptor antibody
    • PTAFR antibody
    • PTAFR_HUMAN antibody
    • RP23-470B20.1 antibody
    see all

Images

  • All lanes : Anti-PAF-R antibody (ab226936) at 1/500 dilution

    Lane 1 : HL-60 (human promyelocytic leukemia cell line) whole cell extract
    Lane 2 : HL-60 membrane extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 39 kDa



    Samples were not boiled.

    10% SDS-PAGE gel.

References

This product has been referenced in:

  • Lou C  et al. Ginkgolide B enhances gemcitabine sensitivity in pancreatic cancer cell lines via inhibiting PAFR/NF-?B pathway. Biomed Pharmacother 109:563-572 (2019). Read more (PubMed: 30399592) »
See 1 Publication for this product

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