Overview

  • Product name

  • Description

    Rabbit polyclonal to PAF1/PD2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PAF1/PD2 aa 475-525.
    Database link: Q9NUU9

  • Positive control

    • Human controls: Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma, Breast Carcinoma, Colon Carcinoma, Laryngeal Squamous Cell Carcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Skin Melanoma and Small Cell Lung Cancer.
  • General notes

    Previously labelled as PAF1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab84914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo and in vitro.
    • Sequence similarities

      Belongs to the PAF1 family.
    • Cellular localization

      Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin.
    • Information by UniProt
    • Database links

    • Alternative names

      • F23149 1 antibody
      • FLJ11123 antibody
      • hPAF1 antibody
      • PAF 1 antibody
      • PAF1 antibody
      • Paf1 RNA polymerase II associated factor homolog antibody
      • PAF1_HUMAN antibody
      • Pancreatic differentiation protein 2 antibody
      • PD 2 antibody
      • PD2 antibody
      • PD2 protein antibody
      • RNA polymerase II associated factor homolog antibody
      • RNA polymerase II-associated factor 1 homolog antibody
      see all

    Images

    • ab84914, at a 1/250 dilution, staining PAF1/PD2 in formalin fixed, paraffin embedded human small cell lung cancer by Immunohistochemistry using DAB staining.

    • ab84914, at 1/250 dilution, staining PAF1/PD2 in formalin fixed, paraffin embedded human pancreatic islet cell tumor by Immunohistochemistry using DAB staining.

    References

    ab84914 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab84914.
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