Overview

  • Product name

  • Description

    Rabbit polyclonal to PAICS/PAIS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein corresponding to Human PAICS/PAIS aa 250-425 (C terminal).
    Database link: P22234

  • Positive control

    • Jurkat, 293T, SW620, Raji and HeLa cell extracts; U2OS cells.
  • General notes

     This product was previously labelled as PAICS

     

Properties

Applications

Our Abpromise guarantee covers the use of ab210806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 47 kDa.
ICC/IF 1/10 - 1/100.
IHC-P 1/50 - 1/200.

Target

  • Pathway

    Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
    Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.
  • Sequence similarities

    In the N-terminal section; belongs to the SAICAR synthetase family.
    In the C-terminal section; belongs to the AIR carboxylase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADE2 antibody
    • ADE2H1 antibody
    • AIR carboxylase antibody
    • AIRC antibody
    • DKFZp781N1372 antibody
    • MGC1343 antibody
    • MGC5024 antibody
    • Multifunctional protein ADE2 antibody
    • Multifunctional protein ADE2H1 antibody
    • Paics antibody
    • PAIS antibody
    • Phosphoribosylaminoimidazole carboxylase antibody
    • Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody
    • PUR6_HUMAN antibody
    • SAICAR synthetase antibody
    see all

Images

  • All lanes : Anti-PAICS/PAIS antibody (ab210806) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : 293T cell extract
    Lane 3 : SW620 cell extract
    Lane 4 : Raji cell extract
    Lane 5 : HeLa cell extract

    Predicted band size: 47 kDa

  • Immunofluorescent analysis of U2OS cells labeling PAICS/PAIS with ab210806 at 1/10 dilution. Blue: DAPI for nuclear staining.

References

ab210806 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab210806.
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