Overview

  • Product name

  • Description

    Rabbit polyclonal to PAICS/PAIS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment within Human PAICS/PAIS (internal sequence). The exact sequence is proprietary.
    Database link: P22234

  • Positive control

    • WB: Jurkat whole cell lysate. IHC-P: RT2 xenograft and HBL435 xenograft tissues.
  • General notes

     This product was previously labelled as PAICS

     

Properties

Applications

Our Abpromise guarantee covers the use of ab229531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/5000 - 1/20000. Predicted molecular weight: 47 kDa.

Target

  • Pathway

    Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
    Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.
  • Sequence similarities

    In the N-terminal section; belongs to the SAICAR synthetase family.
    In the C-terminal section; belongs to the AIR carboxylase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADE2 antibody
    • ADE2H1 antibody
    • AIR carboxylase antibody
    • AIRC antibody
    • DKFZp781N1372 antibody
    • MGC1343 antibody
    • MGC5024 antibody
    • Multifunctional protein ADE2 antibody
    • Multifunctional protein ADE2H1 antibody
    • Paics antibody
    • PAIS antibody
    • Phosphoribosylaminoimidazole carboxylase antibody
    • Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody
    • PUR6_HUMAN antibody
    • SAICAR synthetase antibody
    see all

Images

  • Anti-PAICS/PAIS antibody (ab229531) at 1/10000 dilution + Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate at 30 µg

    Predicted band size: 47 kDa



    10% SDS-PAGE gel.

  • Paraffin-embedded RT2 xenograft tissue stained for PAICS/PAIS using ab229531 at 1/500 dilution in immunohistochemical analysis.

  • Paraffin-embedded HBL435 xenograft stained for PAICS/PAIS using ab229531 at 1/500 dilution in immunohistochemical analysis.

References

ab229531 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229531.
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