Overview

  • Product name

    Anti-pan Cadherin antibody
    See all pan Cadherin primary antibodies
  • Description

    Rabbit polyclonal to pan Cadherin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Chicken pan Cadherin aa 850 to the C-terminus (C terminal). The exact sequence is proprietary. Immunogen is from chicken N-cadherin.
    Database link: P10288

  • Positive control

    • IHC-P: Human skin tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis.
  • Database links

  • Alternative names

    • Cadherin antibody
    • CDH3 antibody
    • CDHP antibody
    • 7B4 antigen antibody
    • Cadherin-1 antibody
    • Cadherin-2 antibody
    • Cadherin-3 antibody
    • Cadherin-4 antibody
    • Cadherin-5 antibody
    • CAM 120/80 antibody
    • CD144 antibody
    • CD324 antibody
    • CD325 antibody
    • Cdh4 antibody
    • CDH5 antibody
    • CDHE antibody
    • CDHN antibody
    • E-cadherin antibody
    • Epithelial cadherin antibody
    • N-cadherin antibody
    • NCAD antibody
    • Neural cadherin antibody
    • P-cadherin antibody
    • Placental cadherin antibody
    • UVO antibody
    • Uvomorulin antibody
    • Vascular endothelial cadherin antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human skin tissue stained for pan Cadherin using ab230459 at 1/100 dilution in immunohistochemical analysis.

References

ab230459 has not yet been referenced specifically in any publications.

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