Anti-pan Cadherin antibody [CH-19] (ab6528)

Mouse monoclonal pan Cadherin antibody [CH-19]. Validated in WB, IHC, ICC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Rabbit, Goat, Chicken, Guinea pig, Hamster, Cow, Cat, Dog, Human, Pig and more.

Publishing research using ab6528? Please let us know so that we can cite the reference in this datasheet.

ab6528 has been referenced in 71 publications.

  • Ye Y  et al. UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway. Cancer Manag Res 11:2339-2348 (2019). PubMed: 30962721
  • Vaddi DR  et al. Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells. PLoS One 14:e0215905 (2019). PubMed: 31017964
  • Xiong Y  et al. Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide-induced intestinal injury. Mol Med Rep 18:2171-2181 (2018). PubMed: 29901151
  • Wang Y  et al. Myosin Heavy Chain 10 (MYH10) Gene Silencing Reduces Cell Migration and Invasion in the Glioma Cell Lines U251, T98G, and SHG44 by Inhibiting the Wnt/ß-Catenin Pathway. Med Sci Monit 24:9110-9119 (2018). PubMed: 30552850
  • Schrade K  et al. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One 13:e0191423 (2018). PubMed: 29373579
  • Boutin ME  et al. A three-dimensional neural spheroid model for capillary-like network formation. J Neurosci Methods 299:55-63 (2018). IHC-P . PubMed: 28143748
  • Tian L  et al. Calotropin regulates the apoptosis of non-small cell cancer by regulating the cytotoxic T-lymphocyte associated antigen 4-mediated TGF-ß/ERK signaling pathway. Mol Med Rep 17:7683-7691 (2018). PubMed: 29620207
  • Zhang C  et al. GSK3ß inhibits epithelial-mesenchymal transition via the Wnt/ß-catenin and PI3K/Akt pathways. Int J Ophthalmol 11:1120-1128 (2018). PubMed: 30046527
  • Haghani A  et al. Edible bird's nest modulate intracellular molecular pathways of influenza A virus infected cells. BMC Complement Altern Med 17:22 (2017). PubMed: 28056926
  • Serrano-Pozo A  et al. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-ß Peptide Generation In Vivo. PLoS One 12:e0170345 (2017). WB ; Mouse . PubMed: 28099462
  • Bagh MB  et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun 8:14612 (2017). WB ; Mouse . PubMed: 28266544
  • Chen Z  et al. LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-ß-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway. Exp Ther Med 14:4951-4957 (2017). PubMed: 29201199
  • Liu Y  et al. Engineering cell signaling using tunable CRISPR-Cpf1-based transcription factors. Nat Commun 8:2095 (2017). PubMed: 29235474
  • Plössl K  et al. Retinoschisin is linked to retinal Na/K-ATPase signaling and localization. Mol Biol Cell 28:2178-2189 (2017). PubMed: 28615319
  • Guichard A  et al. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. PLoS Pathog 13:e1006603 (2017). PubMed: 28945820
  • Sakuma K  et al. p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice. J Cachexia Sarcopenia Muscle 7:204-12 (2016). Mouse . PubMed: 27493873
  • Swinford-Jackson SE  et al. Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system. Neuroscience 324:50-61 (2016). PubMed: 26926963
  • Bender G  et al. Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS. J Biol Chem 291:19413-24 (2016). PubMed: 27435673
  • Kulshrestha A  et al. Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer. Oncotarget 6:3797-810 (2015). IHC-P ; Human . PubMed: 25686833
  • Zacherl S  et al. A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2. J Biol Chem 290:3654-65 (2015). Human . PubMed: 25533462
  • Anastasio NC  et al. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. ACS Chem Neurosci 6:1248-58 (2015). PubMed: 26120876
  • Fink LH  et al. Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System. Neuropsychopharmacology 40:1957-68 (2015). PubMed: 25666313
  • Boutin ME & Hoffman-Kim D Application and assessment of optical clearing methods for imaging of tissue-engineered neural stem cell spheres. Tissue Eng Part C Methods 21:292-302 (2015). PubMed: 25128373
  • Yu ML  et al. The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology. Biomed Res Int 2015:582359 (2015). PubMed: 26417596
  • Anastasio NC  et al. Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. Neuropsychopharmacology 39:370-82 (2014). PubMed: 23939424
  • Qiu X  et al. Aerosol azacytidine inhibits orthotopic lung cancers in mice through Its DNA demethylation and gene reactivation effects. PLoS One 9:e109874 (2014). WB ; Human . PubMed: 25347303
  • Kempf A  et al. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS Biol 12:e1001763 (2014). WB ; Human . PubMed: 24453941
  • Anastasio NC  et al. Variation within the serotonin (5-HT) 5-HT2C receptor system aligns with vulnerability to cocaine cue reactivity. Transl Psychiatry 4:e369 (2014). WB ; Rat . PubMed: 24618688
  • Monteiro J  et al. V-ATPase proton pumping activity is required for adult zebrafish appendage regeneration. PLoS One 9:e92594 (2014). IHC (PFA fixed) ; Zebrafish . PubMed: 24671205
  • Orbelyan GA  et al. Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12. J Immunol 193:610-6 (2014). Human . PubMed: 24935923
  • Mehrbod P  et al. Simvastatin modulates cellular components in influenza A virus-infected cells. Int J Mol Med 34:61-73 (2014). WB ; Dog . PubMed: 24788303
  • Gallego-Iradi C  et al. KCNC3(R420H), a K(+) channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking. Neurobiol Dis 71:270-9 (2014). ICC/IF ; Monkey . PubMed: 25152487
  • Oaks AW  et al. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS One 8:e60378 (2013). WB ; Mouse . PubMed: 23560093
  • Ngamjariyawat A  et al. Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death. PLoS One 8:e61828 (2013). ICC/IF ; Mouse . PubMed: 23613946
  • Burg VK  et al. Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study. J Neurosci 33:16072-87 (2013). PubMed: 24107941
  • Czeredys M  et al. Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease. Front Mol Neurosci 6:42 (2013). WB ; Rat . PubMed: 24324398
  • Puehringer D  et al. EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Nat Neurosci 16:407-15 (2013). PubMed: 23416450
  • Azab AK  et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood 119:5782-94 (2012). ICC/IF ; Mouse . PubMed: 22394600
  • Yoo SK  et al. Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol 199:225-34 (2012). IF ; Zebrafish . PubMed: 23045550
  • Grünewald E  et al. Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain. ACS Chem Neurosci 3:459-72 (2012). PubMed: 22860215
  • Jin M  et al. Determinants of TRPV4 Activity following Selective Activation by Small Molecule Agonist GSK1016790A. PLoS One 6:e16713 (2011). WB ; Human . PubMed: 21339821
  • Kanojia D  et al. Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity. Am J Pathol 178:1009-20 (2011). ICC/IF ; Human . PubMed: 21356354
  • Grimm MO  et al. Docosahexaenoic Acid Reduces Amyloid {beta} Production via Multiple Pleiotropic Mechanisms. J Biol Chem 286:14028-39 (2011). WB ; Human . PubMed: 21324907
  • Miyazaki M  et al. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes. FEBS J 277:2180-91 (2010). WB ; Rat . PubMed: 20412061
  • Sayer NM  et al. Direct binding of sulfur mustard and chloroethyl ethyl sulphide to human cell membrane-associated proteins; implications for sulfur mustard pathology. J Chromatogr B Analyt Technol Biomed Life Sci 878:1426-32 (2010). WB ; Human . PubMed: 20004628
  • Neussert R  et al. The presence of bestrophin-1 modulates the Ca2+ recruitment from Ca2+ stores in the ER. Pflugers Arch 460:163-75 (2010). WB ; Mouse . PubMed: 20411394
  • Diekmann S  et al. Pelizaeus-Merzbacher-like disease is caused not only by a loss of connexin47 function but also by a hemichannel dysfunction. Eur J Hum Genet 18:985-92 (2010). ICC/IF ; Human . PubMed: 20442743
  • Hong HM  et al. A novel mutation in the connexin 29 gene may contribute to nonsyndromic hearing loss. Hum Genet 127:191-9 (2010). PubMed: 19876648
  • Su CC  et al. Mutation R184Q of connexin 26 in hearing loss patients has a dominant-negative effect on connexin 26 and connexin 30. Eur J Hum Genet 18:1061-4 (2010). ICC/IF ; Human . PubMed: 20442751
  • Schapitz IU  et al. Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci 30:12733-44 (2010). WB ; Mouse, Rat . PubMed: 20861378
  • Zhu H  et al. Arrhythmogenic properties of dismantling cadherin-mediated adhesion in murine hearts. J Biomed Res 24:292-300 (2010). PubMed: 23554643
  • Jha MK  et al. Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels. Nat Immunol 10:1275-82 (2009). PubMed: 19838200
  • Havasi A  et al. Hsp27 inhibits sublethal, Src-mediated renal epithelial cell injury. Am J Physiol Renal Physiol 297:F760-8 (2009). IF . PubMed: 19553351
  • Murthy V  et al. Activity of nAChRs containing alpha9 subunits modulates synapse stabilization via bidirectional signaling programs. Dev Neurobiol 69:931-49 (2009). IHC-P ; Mouse . PubMed: 19790106
  • Schwarzer W  et al. A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes. Hum Mol Genet 18:4013-21 (2009). WB ; Human . PubMed: 19640924
  • Bae GU  et al. Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro. Mol Biol Cell 20:4920-31 (2009). WB ; Mouse . PubMed: 19812254
  • Black MA  et al. Role of polysialylated neural cell adhesion molecule in rapid eye movement sleep regulation in rats. Eur J Neurosci 30:2190-204 (2009). WB ; Rat . PubMed: 20128854
  • Bae GU  et al. Regulation of Myoblast Motility and Fusion by the CXCR4-associated Sialomucin, CD164. J Biol Chem 283:8301-9 (2008). WB ; Mouse . PubMed: 18227060
  • Grimm MO  et al. Independent Inhibition of Alzheimer Disease {beta}- and {gamma}-Secretase Cleavage by Lowered Cholesterol Levels. J Biol Chem 283:11302-11 (2008). WB ; Human . PubMed: 18308724
  • Wang CC  et al. Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction. Cardiovasc Res 77:515-24 (2008). PubMed: 18006453
  • Pang Y  et al. Estrogen signaling characteristics of Atlantic croaker GPR30 and evidence it is involved in maintenance of oocyte meiotic arrest. Endocrinology : (2008). ICC/IF ; Human . PubMed: 18420744
  • Fibbi B  et al. Atorvastatin but not elocalcitol increases sildenafil responsiveness in spontaneously hypertensive rats by regulating the RhoA/ROCK pathway. J Androl 29:70-84 (2008). PubMed: 17699803
  • Otto C  et al. GPR30 localizes to the endoplasmic reticulum and is not activated by estradiol. Endocrinology : (2008). PubMed: 18566127
  • Rock MJ  et al. Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet 40:999-1003 (2008). WB ; Human . PubMed: 18587396
  • Matza D  et al. A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation. Immunity 28:64-74 (2008). PubMed: 18191595
  • Gellersen B  et al. Expression of the metastasis suppressor KAI1 in decidual cells at the human maternal-fetal interface: Regulation and functional implications. Am J Pathol 170:126-39 (2007). PubMed: 17200188
  • Whitaker HC  et al. Labeling and identification of LNCaP cell surface proteins: a pilot study. Prostate 67:943-54 (2007). PubMed: 17440980
  • Motazacker MM  et al. A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation. Am J Hum Genet 81:792-8 (2007). PubMed: 17847003
  • Lester RD  et al. uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. J Cell Biol 178:425-36 (2007). WB ; Human . PubMed: 17664334
  • Dai X & Galligan JJ Differential trafficking and desensitization of human ET(A) and ET(B) receptors expressed in HEK 293 cells. Exp Biol Med (Maywood) 231:746-51 (2006). ICC/IF ; Human . PubMed: 16740992
  • Chapman SC & Woodruff TK Betaglycan localization in the female rat pituitary: implications for the regulation of follicle-stimulating hormone by inhibin. Endocrinology 144:5640-9 (2003). PubMed: 14500575

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