Overview

  • Product name
    Anti-PANK1 antibody - N-terminal
    See all PANK1 primary antibodies
  • Description
    Rabbit polyclonal to PANK1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human PANK1 aa 83-112 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8TE04

  • Positive control
    • MCF7 cell line and Mouse spleen tissue lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab175850 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab175850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 64 kDa.

Target

  • Function
    Plays a role in the physiological regulation of the intracellular CoA concentration.
  • Tissue specificity
    Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
  • Pathway
    Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
  • Sequence similarities
    Belongs to the type II pantothenate kinase family.
  • Domain
    The N-terminal extension, present in isoform 1 may be the regulatory domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • coaA antibody
    • hPanK antibody
    • hPanK1 antibody
    • PANK antibody
    • PANK1 antibody
    • PANK1_HUMAN antibody
    • PANK1a antibody
    • PANK1b antibody
    • PanK1beta antibody
    • Pantothenate kinase 1 antibody
    • Pantothenate kinase antibody
    • Pantothenic acid kinase 1 antibody
    see all

Images

  • All lanes : Anti-PANK1 antibody - N-terminal (ab175850) at 1/1000 dilution

    Lane 1 : MCF7 cell line lysate
    Lane 2 : Mouse spleen tissue lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 64 kDa

References

ab175850 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab175850.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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