Product namePantoprazole sodium sesquihydrate, H+/K+ ATPase proton pump inhibitor
DescriptionH+/K+ ATPase proton pump inhibitor
Biological descriptionH+/K+ ATPase proton pump inhibitor. Anti-inflammatory. Inhibits hydroxyl radicals and gastric acid secretion. Orally active. Active in vivo and in vitro.
Chemical name6-(Difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1,2-dihydrobenzimidazol-3-ide sodium salt sesquihydrate
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water or ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Ion pumps / transporter
- H+/K+ ATPase
This product has been referenced in:
- Simon WA et al. Hydroxyl radical scavenging reactivity of proton pump inhibitors. Biochem Pharmacol 71:1337-41 (2006). Read more (PubMed: 16494850) »
- Sachs G et al. The pharmacology of the gastric acid pump: the H+,K+ ATPase. Annu Rev Pharmacol Toxicol 35:277-305 (1995). Read more (PubMed: 7598495) »
- Tucker GT The interaction of proton pump inhibitors with cytochromes P450. Aliment Pharmacol Ther 8 Suppl 1:33-8 (1994). Read more (PubMed: 8180292) »