Key features and details
- Rabbit polyclonal to PAPP A
- Suitable for: IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 0.1% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50 – 1/200
FunctionMetalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Tissue specificityHigh levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts.
Sequence similaritiesBelongs to the peptidase M43B family.
Contains 5 Sushi (CCP/SCR) domains.
Developmental stagePresent in serum and placenta during pregnancy; levels increase throughout pregnancy.
modificationsThere appear to be no free sulfhydryl groups.
- Information by UniProt
- ASBABP2 antibody
- Aspecific BCL2 ARE binding protein 2 antibody
- Differentially placenta 1 expressed protein antibody
ab203683 has not yet been referenced specifically in any publications.