Overview

  • Product name

    Anti-PAPP A2 antibody [ABM4C62]
    See all PAPP A2 primary antibodies
  • Description

    Mouse monoclonal [ABM4C62] to PAPP A2
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human PAPP A2 aa 332-561.
    Database link: Q9BXP8

  • Positive control

    • IHC-P: Human placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab228434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml.

Target

  • Function

    Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.
  • Tissue specificity

    Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.
  • Sequence similarities

    Belongs to the peptidase M43B family.
    Contains 5 Sushi (CCP/SCR) domains.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • PAPPA 2 antibody
    • PAPP E antibody
    • PAPP-A2 antibody
    • PAPP-E antibody
    • PAPP2_HUMAN antibody
    • PAPPA2 antibody
    • Pappalysin 2 antibody
    • Pappalysin-2 antibody
    • PLAC3 antibody
    • Pregnancy associated plasma protein A2 antibody
    • Pregnancy associated plasma protein E1 antibody
    • Pregnancy-associated plasma protein A2 antibody
    • Pregnancy-associated plasma protein E1 antibody
    see all

Images

  • Human placenta tissue stained for PAPP A2 using ab228434 at 5 µg/ml in immunohistochemical analysis.

References

ab228434 has not yet been referenced specifically in any publications.

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