Overview

  • Product name

    Anti-PAR2 antibody - Extracellular domain
    See all PAR2 primary antibodies
  • Description

    Rabbit polyclonal to PAR2 - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except NMBR (39%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Hamster, Pig, Monkey, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human PAR2 (extracellular). 18 amino acid peptide from the 2nd extracellular domain. (NP_005233.3)
    Database link: P55085

  • Positive control

    • Human kidney tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for trypsin and trypsin-like enzymes coupled to G proteins that stimulate phosphoinositide hydrolysis. May have a role in the regulation of vascular tone.
  • Tissue specificity

    Widely expressed in tissues with especially high levels in pancreas, liver, kidney, small intestine, and colon. Moderate expression is detected in many organs, but none in brain or skeletal muscle.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Coagulation factor II receptor like 1 antibody
    • Coagulation factor II receptor-like 1 antibody
    • Coagulation factor II thrombin receptor like 1 antibody
    • F2RL1 antibody
    • G protein coupled receptor 11 antibody
    • G-protein coupled receptor 11 antibody
    • GPR11 antibody
    • PAR 2 antibody
    • PAR-2 antibody
    • PAR2_HUMAN antibody
    • Protease activated receptor 2 antibody
    • Proteinase activated receptor 2 antibody
    • Proteinase-activated receptor 2 antibody
    • Thrombin receptor like 1 antibody
    • Thrombin receptor-like 1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling PAR2 with ab188755 at 10 µg/ml.

References

ab188755 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab188755.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up