Anti-Parathyroid Hormone antibody [3H9] - N-terminal (ab218493)
Key features and details
- Mouse monoclonal [3H9] to Parathyroid Hormone - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
Overview
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Product name
Anti-Parathyroid Hormone antibody [3H9] - N-terminal
See all Parathyroid Hormone primary antibodies -
Description
Mouse monoclonal [3H9] to Parathyroid Hormone - N-terminal -
Host species
Mouse -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog, Pig, Orangutan -
Immunogen
Synthetic peptide within Human Parathyroid Hormone. The exact sequence is proprietary. (From within amino acids 1 to 34 of mature Parathyroid Hormone. Conjugated to a carrier).
Database link: P01270 -
Positive control
- Human parathyroid tissue.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
ab218493 was purified from Bioreactor Concentrate by Protein A/G. -
Clonality
Monoclonal -
Clone number
3H9 -
Isotype
IgG2b -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab218493 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P | Use a concentration of 0.25 - 0.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. (Primary incubation for 30 minutes at RT). |
Target
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Function
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. -
Involvement in disease
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. -
Sequence similarities
Belongs to the parathyroid hormone family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 280903 Cow
- Entrez Gene: 403986 Dog
- Entrez Gene: 5741 Human
- Entrez Gene: 19226 Mouse
- Entrez Gene: 100462630 Orangutan
- Entrez Gene: 399502 Pig
- Entrez Gene: 100351309 Rabbit
- Entrez Gene: 24694 Rat
see all -
Alternative names
- hPTH antibody
- Parathormone antibody
- Parathyrin antibody
see all
Images
Datasheets and documents
References (0)
ab218493 has not yet been referenced specifically in any publications.