Anti-Parathyroid Hormone antibody [D1.1] (ab14498)
Key features and details
- Mouse monoclonal [D1.1] to Parathyroid Hormone
- Suitable for: IHC-P, ELISA, IHC-Fr
- Reacts with: Dog, Human
- Isotype: IgG1
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Parathyroid Hormone antibody [D1.1]
See all Parathyroid Hormone primary antibodies -
Description
Mouse monoclonal [D1.1] to Parathyroid Hormone -
Host species
Mouse -
Tested applications
Suitable for: IHC-P, ELISA, IHC-Frmore details -
Species reactivity
Reacts with: Dog, Human
Predicted to work with: Cow, Cynomolgus monkey -
Immunogen
Synthetic peptide:
KKEDNVLVESHEKSLGEADKADVNVLTKAKSQ
, corresponding to amino acids 53-84 of Human Parathyroid Hormone. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
D1.1 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab14498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P | (1) |
Use at an assay dependent concentration.
|
ELISA |
Use at an assay dependent concentration.
Use at a concentration of 500 ng/ml. |
|
IHC-Fr |
Use at an assay dependent concentration.
ILMA: Use at a concentration of 500 ng/ml. |
Notes |
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IHC-P
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. Use at a concentration of 500 ng/ml. |
IHC-Fr
Use at an assay dependent concentration. ILMA: Use at a concentration of 500 ng/ml. |
Target
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Function
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. -
Involvement in disease
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. -
Sequence similarities
Belongs to the parathyroid hormone family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 280903 Cow
- Entrez Gene: 403986 Dog
- Entrez Gene: 5741 Human
- Omim: 168450 Human
- SwissProt: P01268 Cow
- SwissProt: P52212 Dog
- SwissProt: P01270 Human
- Unigene: 37045 Human
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Alternative names
- hPTH antibody
- Parathormone antibody
- Parathyrin antibody
see all
Datasheets and documents
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Datasheet download
References (0)
ab14498 has not yet been referenced specifically in any publications.