Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab176393)
Key features and details
- Rabbit polyclonal to Parathyroid Hormone Receptor 1/PTH1R
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Parathyroid Hormone Receptor 1/PTH1R antibody
See all Parathyroid Hormone Receptor 1/PTH1R primary antibodies -
Description
Rabbit polyclonal to Parathyroid Hormone Receptor 1/PTH1R -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Dog, Pig, Orangutan -
Immunogen
Synthetic peptide corresponding to Human Parathyroid Hormone Receptor 1/PTH1R aa 388-406 (C terminal).
Sequence:KLRETNAGRCDTRQQYRKL
Database link: Q03431 -
Positive control
- SKOV, U20S, HeLa and SMMC cell lysates; Human thyroid cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab176393 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 66 kDa.
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IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 66 kDa. |
IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Expressed in most tissues. Most abundant in kidney, bone and liver. -
Involvement in disease
Jansen metaphyseal chondrodysplasia
Chondrodysplasia Blomstrand type
Enchondromatosis multiple
Eiken skeletal dysplasia
Primary failure of tooth eruption -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 507783 Cow
- Entrez Gene: 403779 Dog
- Entrez Gene: 5745 Human
- Entrez Gene: 19228 Mouse
- Entrez Gene: 100190839 Orangutan
- Entrez Gene: 397675 Pig
- Entrez Gene: 56813 Rat
- Omim: 168468 Human
see all -
Alternative names
- MGC138426 antibody
- MGC138452 antibody
- Parathyroid hormone 1 receptor antibody
see all
Images
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Immunohistochemical analysis of Paraffin-embedded Human thyroid cancer tissue labeling Parathyroid Hormone Receptor 1/PTH1R with ab176393 at 1 µg/ml.
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All lanes : Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab176393) at 0.5 µg/ml
Lane 1 : SKOV cell lysates
Lane 2 : U20S cell lysates
Lane 3 : HeLa cell lysates
Lane 4 : SMMC cell lysates
Predicted band size: 66 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab176393 has not yet been referenced specifically in any publications.