Key features and details
- Rabbit polyclonal to PARC
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PARC antibody
DescriptionRabbit polyclonal to PARC
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
17 amino acid synthetic peptide, conjugated to KLH, from the C terminal region of Human PARC
- Human testis tissue
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab115631 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionCytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity.
Tissue specificityUbiquitously expressed in all tissues with highest expression in testis brain and kidney.
Sequence similaritiesBelongs to the cullin family.
Contains 1 DOC domain.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers.
DomainThe IBR domain is required for interaction with UBCH7 and UBCH8.
modificationsIn vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin.
- Information by UniProt
- CUL-9 antibody
- Cul9 antibody
- CUL9_HUMAN antibody
ab115631 has not yet been referenced specifically in any publications.