Overview

  • Product name

    Paromomycin sulfate, aminoglycoside antibiotic
  • Description

    Broad spectrum aminoglycoside antibiotic
  • Biological description

    Broad spectrum aminoglycoside antibiotic. Protein synthesis inhibitor. Binds to 16S ribosomal RNA. Orally active.
  • Purity

    > 98%
  • CAS Number

    1263-89-4
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    713.71
  • Molecular formula

    C23H45N5O14
  • PubChem identifier

    441375
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O) O)N)O)O)N.OS(=O)(=O)O
  • Source

    Streptomyces rimosus

  • Research areas

References

This product has been referenced in:

  • Begley U  et al. A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-a. EMBO Mol Med 5:366-83 (2013). Read more (PubMed: 23381944) »
  • Muijsers M  et al. Antibacterial therapeutics for the treatment of chytrid infection in amphibians: Columbus's egg? BMC Vet Res 8:175 (2012). Read more (PubMed: 23009707) »
  • Goossens J  et al. Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin. BMC Vet Res 8:245 (2012). Read more (PubMed: 23244712) »

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