Anti-Partitioning defective 3-like protein antibody (ab122264)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-Partitioning defective 3-like protein antibody
See all Partitioning defective 3-like protein primary antibodies -
Description
Rabbit polyclonal to Partitioning defective 3-like protein -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human Partitioning defective 3-like protein aa 1036-1141.
-
Positive control
- Human skin tissue
-
General notes
ab122264 is mono-specific.
Previously labelled as PARD3B.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
ab122264 is mono-specific. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab122264 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. -
Tissue specificity
Highly expressed in kidney, lung and skeletal muscle. Expressed at intermediate levels in brain, heart, placenta, liver and pancreas. Isoform 1 is predominant, while isoform 2 and isoform 3 are expressed at lower levels. -
Sequence similarities
Belongs to the PAR3 family.
Contains 3 PDZ (DHR) domains. -
Domain
The N-terminal part (1-351) part blocks the association of the tight junction marker TJP1 with the cell-cell boundary when it is overexpressed. -
Cellular localization
Endomembrane system. Cell junction. Cell junction > tight junction. Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions. - Information by UniProt
-
Database links
- Entrez Gene: 117583 Human
- SwissProt: Q8TEW8 Human
- Unigene: 657382 Human
- Unigene: 729379 Human
-
Alternative names
- ALS2CR19 antibody
- Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 19 antibody
- Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Partitioning defective 3-like protein antibody (ab122264)ab122264, at 1/10 dilution, staining Partitioning defective 3-like protein in paraffin-embedded Human skin tissue by Immunohistochemistry.
Protocols
Datasheets and documents
References
ab122264 has not yet been referenced specifically in any publications.
