Anti-PARVA antibody (ab154654)
Key features and details
- Rabbit polyclonal to PARVA
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-PARVA antibody
See all PARVA primary antibodies -
Description
Rabbit polyclonal to PARVA -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Cow -
Immunogen
Recombinant fragment corresponding to Human PARVA aa 111-372.
Database link: Q9NVD7 -
Positive control
- HeLa and mouse kidney whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154654 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 42 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 42 kDa. |
Target
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Function
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis. -
Tissue specificity
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. -
Sequence similarities
Belongs to the parvin family.
Contains 2 CH (calponin-homology) domains. -
Cellular localization
Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions. - Information by UniProt
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Database links
- Entrez Gene: 55742 Human
- Entrez Gene: 57342 Mouse
- Entrez Gene: 57341 Rat
- Omim: 608120 Human
- SwissProt: Q9NVD7 Human
- SwissProt: Q9EPC1 Mouse
- SwissProt: Q9HB97 Rat
- Unigene: 432914 Human
see all -
Alternative names
- Actopaxin antibody
- Alpha parvin antibody
- Alpha-parvin antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab154654 has been referenced in 2 publications.
- Wu Y et al. The proprotein convertase furin inhibits IL-13-induced inflammation in airway smooth muscle by regulating integrin-associated signaling complexes. Am J Physiol Lung Cell Mol Physiol 321:L102-L115 (2021). PubMed: 34009050
- Huang Y & Gunst SJ Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt. Am J Physiol Lung Cell Mol Physiol 318:L1036-L1055 (2020). PubMed: 32130030