Overview

  • Product name

    Anti-Pasteurella multocida toxin antibody
  • Description

    Rabbit polyclonal to Pasteurella multocida toxin
  • Host species

    Rabbit
  • Specificity

    Reacts with  Pasteurella multocida Toxin (recombinant protein).

  • Tested applications

    Suitable for: ELISA, WBmore details
  • Species reactivity

    Reacts with: Species independent
  • Immunogen

    Recombinant full length protein (His-tag) corresponding to Pasteurella multocida toxin aa 1-1285.
    Database link: P17452

  • Positive control

    • WB: Recombinant Pasteurella multocida toxin.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituents: PBS, 50% Glycerol

    Filter sterilized. Azide and carrier protein free.
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab243178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB 1/500 - 1/1000. Predicted molecular weight: 146 kDa.

Target

  • Relevance

    Pasteurella multocida toxin (PMT) is produced by a gram-negative bacillus, Pasteurella multocida. PMT activates the Gq and G12/13 dependent signaling pathways. Gq and G12/13 are alpha subunits of the GTP trimer bound protein of animal cells. It does not activate the G11 dependent pathway although G11 is similar to Gq. This toxin binds to an unidentified receptor and then is introduced into the cells by endocytosis and starts to function then. Therefore it does not function on cells without the receptor or defective in the endocytosis pathway.
  • Cellular localization

    Cytoplasmic
  • Alternative names

    • Dermonecrotic toxin antibody
    • DNT antibody
    • Mitogenic toxin antibody
    • PMT antibody
    • ToxA antibody
    see all

Images

  • Anti-Pasteurella multocida toxin antibody (ab243178) at 1/1000 dilution + Recombinant P. multocida Toxin. 7.4 ng

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/1000 dilution

    Predicted band size: 146 kDa

References

ab243178 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab243178.
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