Product nameAnti-Pasteurella multocida toxin antibody
DescriptionRabbit polyclonal to Pasteurella multocida toxin
Reacts with Pasteurella multocida Toxin (recombinant protein).
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Species independent
Recombinant full length protein (His-tag) corresponding to Pasteurella multocida toxin aa 1-1285.
Database link: P17452
- WB: Recombinant Pasteurella multocida toxin.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituents: PBS, 50% Glycerol
Filter sterilized. Azide and carrier protein free.
Concentration information loading...
PurityProtein A/G purified
Our Abpromise guarantee covers the use of ab243178 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
|WB||1/500 - 1/1000. Predicted molecular weight: 146 kDa.|
RelevancePasteurella multocida toxin (PMT) is produced by a gram-negative bacillus, Pasteurella multocida. PMT activates the Gq and G12/13 dependent signaling pathways. Gq and G12/13 are alpha subunits of the GTP trimer bound protein of animal cells. It does not activate the G11 dependent pathway although G11 is similar to Gq. This toxin binds to an unidentified receptor and then is introduced into the cells by endocytosis and starts to function then. Therefore it does not function on cells without the receptor or defective in the endocytosis pathway.
- Dermonecrotic toxin antibody
- DNT antibody
- Mitogenic toxin antibody
Anti-Pasteurella multocida toxin antibody (ab243178) at 1/1000 dilution + Recombinant P. multocida Toxin. 7.4 ng
Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/1000 dilution
Predicted band size: 146 kDa
ab243178 has not yet been referenced specifically in any publications.