For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Take a look at our BETA site and see what we’ve done so far.
Search and browse selected products
Purchase these through your usual distributor
This poster highlights some of the key roles of calcium ions in the calcium signaling pathway
Calcium pathway – an overview
Calcium ions play a role in cell excitability, exocytosis, motility, apoptosis, and transcription. Calcium enters the cytoplasm from intracellular stores or from extracellular space, which is driven by a large electrochemical gradient across the plasma membrane.
Calcium can act directly from the activation of ion channels causing signal transduction. It can also act as a second messenger from signal transduction pathways coming from external receptors such as G-protein coupled receptors.
What to expect
Our poster covers calcium movement into and out of the cell and mitochondria. It also covers calcium activation, signal transduction and its role as a second messenger from G-protein coupled receptors.