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Explore the power of knock-out cell lines for your research

Cytokine network interactive poster

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  • Cytokines and inflammation
    • Key cytokines for Th, Tfh, and Treg cell differentiation
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            Explore the cytokine network and find key products to support your research with our interactive poster.

            Download the poster

            Cytokines are the chemical mediators that regulate immune cell homeostasis and provide cells with the ability to communicate with one another1,2. They are produced by many cell populations, including lymphocytes and myeloid cells, to elicit a variety of responses through receptor binding.   

            There are many cytokines with multiple, sometimes unrelated, functions depending on the target cell as well as the presence or absence of other cytokines. These functions include controlling cell proliferation and differentiation as well as the regulation of angiogenesis and immune and inflammatory responses3. If cytokine production in the body is dysregulated, this can lead to autoinflammatory and autoimmune disease, and in some cases, even cancer promotion1.

            What to expect from our poster

            • See how several cells of the immune system, including B cells, T cells, and macrophages, communicate using secreted cytokines
            • Discover high-quality cytokine proteins to advance your research breakthrough


            References

            1. Cytokines in the balance. Nat Immunol 20, 1557 (2019).
            2. Becher, B. et al. Cytokine networks in neuroinflammation Nature Reviews Immunology. 17, 49-59 (2017).
            3. Tisoncik, J.R. et al. Into the Eye of the Cytokine Storm Microbiol Mol Biol Rev. 76(1), 16-32 (2012).
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