Anti-PAX6 antibody (ab5790)

Rabbit polyclonal PAX6 antibody. Validated in WB, IP, IHC, ICC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Sheep, Cow, Dog, Human, Rhesus monkey. Cited in 53 publication(s).

Publishing research using ab5790? Please let us know so that we can cite the reference in this datasheet.

ab5790 has been referenced in 60 publications.

  • Adamo AM  et al. Early Developmental Marginal Zinc Deficiency Affects Neurogenesis Decreasing Neuronal Number and Altering Neuronal Specification in the Adult Rat Brain. Front Cell Neurosci 13:62 (2019). PubMed: 30890920
  • Zou T  et al. Organoid-derived C-Kit+/SSEA4- human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents. Nat Commun 10:1205 (2019). PubMed: 30872578
  • Winokurow N & Schumacher S A role for polycystin-1 and polycystin-2 in neural progenitor cell differentiation. Cell Mol Life Sci N/A:N/A (2019). PubMed: 30895336
  • Bowles KR  et al. Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting. PLoS One 14:e0213374 (2019). PubMed: 30917153
  • Johnson MB  et al. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size. Nature 556:370-375 (2018). PubMed: 29643508
  • Su L  et al. H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor. Nucleic Acids Res 46:8817-8831 (2018). PubMed: 29982651
  • Žunic Išasegi I  et al. Interactive histogenesis of axonal strata and proliferative zones in the human fetal cerebral wall. Brain Struct Funct 223:3919-3943 (2018). PubMed: 30094607
  • Ooki A  et al. Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma. Oncogene N/A:N/A (2018). PubMed: 29980786
  • Xu L  et al. Effect of leukocyte inhibitory factor on neuron differentiation from human induced pluripotent stem cell-derived neural precursor cells. Int J Mol Med 41:2037-2049 (2018). PubMed: 29393372
  • Gould EA  et al. Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone. Elife 7:N/A (2018). PubMed: 29436368
  • Sun C  et al. Transcriptome variations among human embryonic stem cell lines are associated with their differentiation propensity. PLoS One 13:e0192625 (2018). PubMed: 29444173
  • Ferguson R & Subramanian V Embryoid body arrays: Parallel cryosectioning of spheroid/embryoid body samples for medium through-put analysis. Stem Cell Res 28:125-130 (2018). ICC/IF . PubMed: 29455007
  • Nemlich Y  et al. ADAR1-mediated regulation of melanoma invasion. Nat Commun 9:2154 (2018). PubMed: 29855470
  • Yang GS  et al. Mild hypothermia inhibits the Notch 3 and Notch 4 activation and seizure after stroke in the rat model. Pathol Res Pract 214:1008-1016 (2018). WB . PubMed: 29754932
  • Sannan NS  et al. Anolis carolinensis as a model to understand the molecular and cellular basis of foveal development. Exp Eye Res 173:138-147 (2018). IHC-Fr . PubMed: 29775563
  • Shen T  et al. Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. Nucleic Acids Res 46:2290-2307 (2018). PubMed: 29294103
  • Sun J  et al. Differentiation of rat adipose-derived mesenchymal stem cells into corneal-like epithelial cells driven by PAX6. Exp Ther Med 15:1424-1432 (2018). PubMed: 29434727
  • Gillentine MA  et al. Functional Consequences of CHRNA7 Copy-Number Alterations in Induced Pluripotent Stem Cells and Neural Progenitor Cells. Am J Hum Genet 101:874-887 (2017). ICC/IF . PubMed: 29129316
  • He ZQ  et al. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening. Cell Rep 20:2227-2237 (2017). PubMed: 28854370
  • Zhu Z  et al. Zika virus has oncolytic activity against glioblastoma stem cells. J Exp Med 214:2843-2857 (2017). PubMed: 28874392
  • Yuan X  et al. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. PLoS One 12:e0174074 (2017). IF ; Human . PubMed: 28441409
  • Wang Q  et al. Compound anisodine affects the proliferation and calcium overload of hypoxia-induced rat retinal progenitor cells and brain neural stem cells via the p-ERK1/2/HIF-1a/VEGF pathway. Exp Ther Med 14:600-608 (2017). PubMed: 28672973
  • Marei HE  et al. Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential. Sci Rep 7:17504 (2017). PubMed: 29235536
  • Yu CY  et al. The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency. Nat Commun 8:1149 (2017). PubMed: 29074849
  • Song R  et al. Maternal Sevoflurane Exposure Causes Abnormal Development of Fetal Prefrontal Cortex and Induces Cognitive Dysfunction in Offspring. Stem Cells Int 2017:6158468 (2017). IHC-Fr ; Mouse . PubMed: 29098009
  • Gu Q  et al. Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations. Stem Cell Reports 9:366-380 (2017). PubMed: 28506532
  • Momcilovic O  et al. Derivation, Characterization, and Neural Differentiation of Integration-Free Induced Pluripotent Stem Cell Lines from Parkinson's Disease Patients Carrying SNCA, LRRK2, PARK2, and GBA Mutations. PLoS One 11:e0154890 (2016). ICC . PubMed: 27191603
  • Díaz-Balzac CA  et al. Holothurian Nervous System Diversity Revealed by Neuroanatomical Analysis. PLoS One 11:e0151129 (2016). IHC . PubMed: 26987052
  • Cho SH  et al. Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model. BMC Ophthalmol 16:193 (2016). PubMed: 27809828
  • Wu X  et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun 7:10533 (2016). ICC/IF ; Human . PubMed: 26837467
  • Ferraiuolo L  et al. Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism. Proc Natl Acad Sci U S A 113:E6496-E6505 (2016). PubMed: 27688759
  • Wu CY  et al. Retinoic Acid Induces Ubiquitination-Resistant RIP140/LSD1 Complex to Fine-Tune Pax6 Gene in Neuronal Differentiation. Stem Cells 34:114-23 (2016). PubMed: 26372689
  • Wu W  et al. Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures - a new donor for cell therapy. Oncotarget 7:22819-33 (2016). PubMed: 27009841
  • Tsankov AM  et al. A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells. Nat Biotechnol 33:1182-92 (2015). IHC . PubMed: 26501952
  • Cao D  et al. A new tumorsphere culture condition restores potentials of self-renewal and metastasis of primary neuroblastoma in a mouse neuroblastoma model. PLoS One 9:e86813 (2014). IHC-P ; Mouse . PubMed: 24466252
  • De D  et al. Inhibition of master transcription factors in pluripotent cells induces early stage differentiation. Proc Natl Acad Sci U S A 111:1778-83 (2014). PubMed: 24434556
  • Shahi MH  et al. Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells. PLoS One 9:e96593 (2014). WB ; Dog . PubMed: 24810746
  • Wang C  et al. Long-term supranutritional supplementation with selenate decreases hyperglycemia and promotes fatty liver degeneration by inducing hyperinsulinemia in diabetic db/db mice. PLoS One 9:e101315 (2014). WB . PubMed: 24983750
  • Díaz-Balzac CA  et al. Novel markers identify nervous system components of the holothurian nervous system. Invert Neurosci 14:113-25 (2014). PubMed: 24740637
  • Feng N  et al. Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation. Stem Cells Dev 23:515-29 (2014). PubMed: 24138016
  • Momcilovic O  et al. Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem Cells Dev 23:406-20 (2014). PubMed: 24074155
  • Tossas K  et al. Temporal and spatial analysis of enteric nervous system regeneration in the sea cucumber Holothuria glaberrima. Regeneration (Oxf) 1:10-26 (2014). PubMed: 27499861
  • Khalaf-Nazzal R  et al. Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice. PLoS One 8:e72622 (2013). IHC . PubMed: 24023755
  • Harrison-Uy SJ  et al. CoupTFI interacts with retinoic acid signaling during cortical development. PLoS One 8:e58219 (2013). IHC-P ; Mouse . PubMed: 23472160
  • Wang T  et al. Derivation of Neural Stem Cells from Human Adult Peripheral CD34+ Cells for an Autologous Model of Neuroinflammation. PLoS One 8:e81720 (2013). ICC/IF ; Human . PubMed: 24303066
  • Bejjani A  et al. RB116: an RB1+ retinoblastoma cell line expressing primitive markers. Mol Vis 18:2805-13 (2012). PubMed: 23233783
  • Tan SL  et al. Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development 139:3806-16 (2012). ICC/IF ; Mouse . PubMed: 22991445
  • Ross HH  et al. In vivo intermittent hypoxia elicits enhanced expansion and neuronal differentiation in cultured neural progenitors. Exp Neurol 235:238-45 (2012). PubMed: 22366327
  • Yi F  et al. Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells. Protein Cell 3:855-63 (2012). PubMed: 22806248
  • Garcia CM  et al. The function of FGF signaling in the lens placode. Dev Biol 351:176-85 (2011). PubMed: 21223962
  • Coutinho P  et al. Discovery and assessment of conserved Pax6 target genes and enhancers. Genome Res 21:1349-59 (2011). PubMed: 21617155
  • Ban HJ  et al. Genetic and metabolic characterization of insomnia. PLoS One 6:e18455 (2011). ChIP ; Human . PubMed: 21494683
  • Letzen BS  et al. MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells. PLoS One 5:e10480 (2010). ICC/IF ; Human . PubMed: 20463920
  • Billon N  et al. Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development. Genome Biol 11:R80 (2010). WB ; Mouse . PubMed: 20678241
  • Mascarenhas JB  et al. PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene. J Biol Chem 284:27524-32 (2009). WB ; Human, Mouse . PubMed: 19651775
  • Wang K  et al. Dynamic epigenetic regulation of the Oct4 and Nanog regulatory regions during neural differentiation in rhesus nuclear transfer embryonic stem cells. Cloning Stem Cells 11:483-96 (2009). ICC/IF ; Human, Rhesus monkey . PubMed: 20025521
  • Chen Y  et al. Induction of the reelin promoter by retinoic acid is mediated by Sp1. J Neurochem 103:650-65 (2007). PubMed: 17666047
  • McGowan SL  et al. Stem cell markers in the human posterior limbus and corneal endothelium of unwounded and wounded corneas. Mol Vis 13:1984-2000 (2007). IHC-Fr ; Human . PubMed: 17982423
  • Li T  et al. Pax6 regulation in retinal cells by CCCTC binding factor. Invest Ophthalmol Vis Sci 47:5218-26 (2006). IHC-P ; Mouse . PubMed: 17122106
  • Heins N  et al. Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci 5:308-15 (2002). IHC-Fr ; Mouse . PubMed: 11896398

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up