Anti-PBR antibody (ab171776)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-PBR antibody
See all PBR primary antibodies -
Description
Mouse polyclonal to PBR -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length protein corresponding to Human PBR aa 1-169.
Sequence:MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLG PVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFF GARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFATTL NYCVWRDNHGWHGGRRLPE
Database link: AAH01110.1 -
Positive control
- PBR-transfected 293T cell lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Constituent: 100% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab171776 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. |
Target
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Function
Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells. -
Tissue specificity
Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. -
Sequence similarities
Belongs to the TspO/BZRP family. -
Cellular localization
Mitochondrion membrane. - Information by UniProt
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Database links
- Entrez Gene: 706 Human
- Omim: 109610 Human
- SwissProt: B1AH88 Human
- SwissProt: P30536 Human
- Unigene: 202 Human
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Alternative names
- Benzodiazapine receptor (peripheral) antibody
- Benzodiazepine peripheral binding site antibody
- BPBS antibody
see all
Images
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Western blot - Anti-PBR antibody (ab171776)All lanes : Anti-PBR antibody (ab171776) at 1 µg/ml
Lane 1 : PBR-transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution
Predicted band size: 19 kDa
Protocols
Datasheets and documents
References
ab171776 has not yet been referenced specifically in any publications.
