Overview

  • Product name
    Anti-PBR antibody
    See all PBR primary antibodies
  • Description
    Mouse polyclonal to PBR
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human PBR aa 1-169.
    Sequence:

    MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLG PVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFF GARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFATTL NYCVWRDNHGWHGGRRLPE


    Database link: AAH01110.1

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • PBR-transfected 293T cell lysate.

Applications

Our Abpromise guarantee covers the use of ab171776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa.

Target

  • Function
    Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells.
  • Tissue specificity
    Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
  • Sequence similarities
    Belongs to the TspO/BZRP family.
  • Cellular localization
    Mitochondrion membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • Benzodiazapine receptor (peripheral) antibody
      • Benzodiazepine peripheral binding site antibody
      • BPBS antibody
      • BZRP antibody
      • DBI antibody
      • IBP antibody
      • Isoquinoline carboxamide-binding protein antibody
      • MBR antibody
      • mDRC antibody
      • Mitochondrial benzodiazepine receptor antibody
      • PBR antibody
      • PBS antibody
      • Peripheral benzodiazepine receptor antibody
      • Peripheral benzodiazepine receptor-related protein antibody
      • Peripheral type benzodiazepine receptor antibody
      • Peripheral-type benzodiazepine receptor antibody
      • pk18 antibody
      • PKBS antibody
      • PTBR antibody
      • Ptbzr antibody
      • PTBZR02 antibody
      • RATPTBZR02 antibody
      • translocator protein (18kDa) antibody
      • Translocator protein antibody
      • Tspo antibody
      • Tspo1 antibody
      • TSPOA_HUMAN antibody
      see all

    Images

    • Western blot - Anti-PBR antibody (ab171776)
      Western blot - Anti-PBR antibody (ab171776)
      All lanes : Anti-PBR antibody (ab171776) at 1 µg/ml

      Lane 1 : PBR-transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 15 µl per lane.

      Secondary
      All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

      Predicted band size: 19 kDa

    References

    ab171776 has not yet been referenced specifically in any publications.

    Publishing research using ab171776? Please let us know so that we can cite the reference in this datasheet.

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