Overview

  • Product name

    Anti-Pbx3 antibody [EPR2833(2)]
    See all Pbx3 primary antibodies
  • Description

    Rabbit monoclonal [EPR2833(2)] to Pbx3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Pbx3 aa 300-400. The exact sequence is proprietary.

  • Positive control

    • Human fetal brain, A431 and HeLa lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab109173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 47 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.
    • Tissue specificity

      Ubiquitously expressed.
    • Sequence similarities

      Belongs to the TALE/PBX homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Form

      There are 4 isoforms produced by alternative splicing.
    • Alternative names

      • Homeobox protein PBX3 antibody
      • MGC134053 antibody
      • OTTHUMP00000064213 antibody
      • Pbx 3 antibody
      • Pbx3 antibody
      • PBX3_HUMAN antibody
      • Pre B cell leukemia homeobox 3 antibody
      • Pre B cell leukemia transcription factor 3 antibody
      • Pre-B-cell leukemia transcription factor 3 antibody
      • RP11 336P12.1 antibody
      see all

    Images

    • All lanes : Anti-Pbx3 antibody [EPR2833(2)] (ab109173) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : A431 cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 47 kDa

    References

    This product has been referenced in:

    • Xu X  et al. PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion. J Exp Clin Cancer Res 37:158 (2018). Read more (PubMed: 30016974) »
    • Guo H  et al. PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia. Int J Cancer 141:324-335 (2017). Read more (PubMed: 28411381) »
    See all 4 Publications for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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