Anti-PBXIP1/HPIP antibody (ab84752)
Key features and details
- Rabbit polyclonal to PBXIP1/HPIP
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-PBXIP1/HPIP antibody
See all PBXIP1/HPIP primary antibodies -
Description
Rabbit polyclonal to PBXIP1/HPIP -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide corresponding to Human PBXIP1/HPIP.
Database link: NP_079033.3 -
Positive control
- Breast carcinoma, ovarian carcinoma,anaplastic tyroid carcinoma,pancreatic islet cell tumor,stomach adenocarcinoma,testicular seminoma,stomach adenocarcinoma,prostrate carcinoma,linitis plastica stomach cancer,metastatic lymph node,teratoma
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General notes
This product was previously labelled as PBXIP1
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab84752 was affinity purified using an epitope specific to HPIP immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab84752 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Epitope exposure with citrate buffer will enhance staining.
Likely to work on frozen sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Relevance
PBXIP1 is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 also tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. -
Cellular localization
Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus. -
Database links
- Entrez Gene: 57326 Human
- Entrez Gene: 229534 Mouse
- GenBank: NM_020524.2 Human
- SwissProt: Q96AQ6 Human
- SwissProt: Q3TVI8 Mouse
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Alternative names
- 4732463H20Rik antibody
- Hematopoietic PBX interacting protein antibody
- HPIP antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)Detection of mouse HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of mouse teratoma , using ab84752 at a 1/100 dilution.
Detection: DAB staining. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)Detection of human HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of human ovarian carcinoma, using ab84752 at a 1/100 dilution.
Detection: DAB staining. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)Detection of human HPIP by immunohistochemistry immunofluorescence of human ovarian carcinoma, using ab84752 at 1/100 dilution.
Detection: red fluorescent Goat anti-Rabbit IgG diluted 1/100.
Datasheets and documents
References (0)
ab84752 has not yet been referenced specifically in any publications.
