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  1. Link

    pbxip1hpip-antibody-ab84752.pdf

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Signal Transduction Signaling Pathway Nuclear Signaling Nuclear Hormone Receptors Estrogen
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Anti-PBXIP1/HPIP antibody (ab84752)

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  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)

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  • Datasheet
  • References
  • Protocols

Overview

  • Product name

    Anti-PBXIP1/HPIP antibody
    See all PBXIP1/HPIP primary antibodies
  • Description

    Rabbit polyclonal to PBXIP1/HPIP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human PBXIP1/HPIP.
    Database link: NP_079033.3

  • Positive control

    • Breast carcinoma, ovarian carcinoma,anaplastic tyroid carcinoma,pancreatic islet cell tumor,stomach adenocarcinoma,testicular seminoma,stomach adenocarcinoma,prostrate carcinoma,linitis plastica stomach cancer,metastatic lymph node,teratoma
  • General notes

     This product was previously labelled as PBXIP1

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab84752 was affinity purified using an epitope specific to HPIP immobilized on solid support.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human PBXIP1/HPIP protein (ab163534)

Applications

Our Abpromise guarantee covers the use of ab84752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance

      PBXIP1 is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 also tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
    • Cellular localization

      Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus.
    • Database links

      • Entrez Gene: 57326 Human
      • Entrez Gene: 229534 Mouse
      • GenBank: NM_020524.2 Human
      • SwissProt: Q96AQ6 Human
      • SwissProt: Q3TVI8 Mouse
      • Alternative names

        • 4732463H20Rik antibody
        • Hematopoietic PBX interacting protein antibody
        • HPIP antibody
        • MGC38361 antibody
        • Pre B cell leukemia homeobox interacting protein 1 antibody
        • RP11-307C12.2 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Detection of mouse HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of mouse teratoma , using ab84752 at a 1/100 dilution.
        Detection: DAB staining.
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Detection of human HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of human ovarian carcinoma, using ab84752 at a 1/100 dilution.
        Detection: DAB staining.
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PBXIP1/HPIP antibody (ab84752)
        Detection of human HPIP by immunohistochemistry immunofluorescence of human ovarian carcinoma, using ab84752 at 1/100 dilution.
        Detection: red fluorescent Goat anti-Rabbit IgG diluted 1/100.

      Protocols

      • Immunohistochemistry protocols

      Datasheets and documents

      • Datasheet
    • References

      ab84752 has not yet been referenced specifically in any publications.

      Publishing research using ab84752? Please let us know so that we can cite the reference in this datasheet.

      Customer reviews and Q&As

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