Product nameAnti-PC6 antibody - Aminoterminal end
See all PC6 primary antibodies
DescriptionRabbit polyclonal to PC6 - Aminoterminal end
Specificityab39873 recognizes the Amino end of the mature enzyme subtilisin like serine protease PC6.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 2.9% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab39873 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000 - 1/5000. Predicted molecular weight: 101 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionLikely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif.
Tissue specificityExpressed in T-lymphocytes.
Sequence similaritiesBelongs to the peptidase S8 family.
Contains 1 homo B/P domain.
Contains 1 PLAC domain.
DomainThe propeptide domain acts as an intramolecular chaperone assisting the folding of the zymogen within the endoplasmic reticulum.
- Information by UniProt
- FLJ11149 antibody
- FLJ16215 antibody
- hPC6 antibody
This product has been referenced in:
- Sathyamurthy M et al. Characterization and expression of proprotein convertases in CHO cells: Efficient proteolytic maturation of human bone morphogenetic protein-7. Biotechnol Bioeng N/A:N/A (2014). WB . Read more (PubMed: 25219685) »
- Zhou Z et al. The proprotein convertase furin is required for trophoblast syncytialization. Cell Death Dis 4:e593 (2013). WB ; Mouse, Human . Read more (PubMed: 23598405) »