Overview

  • Product name

  • Description

    Rabbit polyclonal to PC7
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human PC7 aa 141-155.
    Sequence:

    RSVHFNDPKYPQQWH


    Database link: Q16549

  • Positive control

    • HEK-293T cell lysate overexpressing Human PC7.
  • General notes

     This product was previously labelled as PCSK7

     

Properties

Applications

Our Abpromise guarantee covers the use of ab213458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 86 kDa.

Target

  • Function

    Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
  • Tissue specificity

    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
  • Sequence similarities

    Belongs to the peptidase S8 family.
    Contains 1 homo B/P domain.
  • Post-translational
    modifications

    Cysteine residues in the cytoplasmic tail are probably palmitoylated.
    N-glycosylated.
  • Cellular localization

    Golgi apparatus > trans-Golgi network membrane. Seems to be localized intracellularly to the trans Golgi network.
  • Information by UniProt
  • Database links

  • Alternative names

    • hPC8 antibody
    • LPC antibody
    • Lymphoma proprotein convertase antibody
    • PC7 antibody
    • PC8 antibody
    • Pcsk7 antibody
    • PCSK7_HUMAN antibody
    • Prohormone convertase 7 antibody
    • Prohormone convertase 8 antibody
    • Proprotein convertase 7 antibody
    • Proprotein convertase 8 antibody
    • Proprotein convertase PC7 antibody
    • Proprotein convertase subtilisin/kexin type 7 antibody
    • SPC7 antibody
    • Subtilisin/kexin-like protease PC7 antibody
    see all

Images

  • Lanes 1-2 : Anti-PC7 antibody (ab213458) at 1/500 dilution
    Lane 3 : Anti-PC7 antibody (ab213458) at 1/1000 dilution

    Lanes 1 & 3 : HEK-293T cell lysate overexpressing Human PC7
    Lane 2 : HEK-293T cell lysate overexpressing Human PC7 with PC7 immunizing peptide (Human, 141-155)

    Secondary
    All lanes : Goat Anti-Rabbit IgG-Peroxidase

    Developed using the ECL technique.

    Predicted band size: 86 kDa

References

ab213458 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab213458.
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