Key features and details
- Rabbit polyclonal to PCCB
- Suitable for: ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-PCCB antibody
See all PCCB primary antibodies
DescriptionRabbit polyclonal to PCCB
Tested applicationsSuitable for: ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein corresponding to Human PCCB aa 1-539.
Database link: P05166
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab186836 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration.|
|WB||1/500 - 1/2000. Predicted molecular weight: 58 kDa.|
PathwayMetabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
Involvement in diseaseDefects in PCCB are the cause of propionic acidemia type II (PA-2) [MIM:606054]. PA-2 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
Sequence similaritiesBelongs to the AccD/PCCB family.
Contains 1 carboxyltransferase domain.
Cellular localizationMitochondrion matrix.
- Information by UniProt
- DKFZp451E113 antibody
- PCCase subunit beta antibody
- pccB antibody
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab186836. Blue DAPI for nuclear staining.
All lanes : Anti-PCCB antibody (ab186836) at 1/500 dilution
Lane 1 : Extracts from HT29 cell line
Lane 2 : Extracts from mouse liver
Lane 3 : Extracts from mouse kidney
Lane 4 : Extracts from mouse heart
Predicted band size: 58 kDa
ab186836 has not yet been referenced specifically in any publications.