Anti-PCDH17 antibody (ab128815)
Key features and details
- Goat polyclonal to PCDH17
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
-
Product name
Anti-PCDH17 antibody -
Description
Goat polyclonal to PCDH17 -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat, Cow, Human, Pig, Chinese hamster -
Immunogen
Synthetic peptide:
C-RVFADVHSRASRDS
, corresponding to C terminal amino acids 1098-1111 of Human PCDH17 (NP_001035519.1). -
Positive control
- Mouse fetal brain lysate
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab128815 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 126 kDa).
1 hour primary incubation is recommended for this product. |
Notes |
---|
WB
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 126 kDa). 1 hour primary incubation is recommended for this product. |
Target
-
Function
Potential calcium-dependent cell-adhesion protein. -
Sequence similarities
Contains 6 cadherin domains. -
Cellular localization
Cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 27253 Human
- Entrez Gene: 219228 Mouse
- Entrez Gene: 306055 Rat
- Omim: 611760 Human
- SwissProt: O14917 Human
- Unigene: 106511 Human
-
Alternative names
- C030033F14Rik antibody
- Gm78 antibody
- PCD17_HUMAN antibody
see all
Images
-
Anti-PCDH17 antibody (ab128815) at 0.2 µg/ml + Mouse fetal brain lysate in RIPA buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 126 kDa
Observed band size: 150 kDa why is the actual band size different from the predicted?
Exposure time: 1 hour
Datasheets and documents
-
Datasheet download
References (2)
ab128815 has been referenced in 2 publications.
- Liu S et al. PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death. Signal Transduct Target Ther 4:53 (2019). PubMed: 31815010
- Luo M et al. MiR-196b affects the progression and prognosis of human LSCC through targeting PCDH-17. Auris Nasus Larynx N/A:N/A (2018). PubMed: 30454973