Anti-PCDH19 antibody - C-terminal (ab191198)
Key features and details
- Rabbit polyclonal to PCDH19 - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-PCDH19 antibody - C-terminal -
Description
Rabbit polyclonal to PCDH19 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rabbit, Horse, Chimpanzee, Rhesus monkey, Gorilla, Common marmoset, Orangutan, Xenopus tropicalis -
Immunogen
Synthetic peptide within Human PCDH19 aa 1050 to the C-terminus (C terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8TAB3 -
Positive control
- 293T, TCMK-1 and NIH3T3 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7-8 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191198 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2500. Predicted molecular weight: 126 kDa.
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Notes |
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WB
1/500 - 1/2500. Predicted molecular weight: 126 kDa. |
Target
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Function
Potential calcium-dependent cell-adhesion protein. -
Tissue specificity
Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast. -
Involvement in disease
Epileptic encephalopathy, early infantile, 9 -
Sequence similarities
Contains 6 cadherin domains. -
Developmental stage
Expressed in developing cortical plate, amygdala and subcortical regions and in the ganglionic eminence. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 101125719 Gorilla
- Entrez Gene: 100059478 Horse
- Entrez Gene: 57526 Human
- Entrez Gene: 279653 Mouse
- Omim: 300460 Human
- SwissProt: Q8TAB3 Human
- SwissProt: Q80TF3 Mouse
- Unigene: 4993 Human
see all -
Alternative names
- KIAA1313 antibody
- PCD19_HUMAN antibody
- PCDH19 antibody
see all
Images
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All lanes : Anti-PCDH19 antibody - C-terminal (ab191198) at 1 mg/ml
Lane 1 : Whole cell lysate from HeLa cells in RIPA buffer at 50 µg
Lane 2 : Whole cell lysate from 293T cells in RIPA buffer at 50 µg
Lane 3 : Whole cell lysate from Jurkat cells in RIPA buffer at 50 µg
Lane 4 : Whole cell lysate from TCMK-1 cells in NETN buffer at 10 µg
Lane 5 : Whole cell lysate from NIH3T3 cells in NETN buffer at 10 µg
Predicted band size: 126 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab191198 has been referenced in 1 publication.
- Wu H et al. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Mol Brain 14:113 (2021). PubMed: 34261484