Recombinant
RabMAb

Recombinant Anti-PCPTP1/PTPRQ antibody [EPR13188] (ab180134)

Overview

  • Product name

    Anti-PCPTP1/PTPRQ antibody [EPR13188]
    See all PCPTP1/PTPRQ primary antibodies
  • Description

    Rabbit monoclonal [EPR13188] to PCPTP1/PTPRQ
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PCPTP1/PTPRQ aa 1-100. The exact sequence is proprietary.
    Database link: Q15256

  • Positive control

    • Human cerebellum, mouse and rat brain lysates.
  • General notes

     

     

     This product was previously labelled as PCPTP1

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    EPR13188
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab180134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 74 kDa.

Target

  • Function

    Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
  • Tissue specificity

    Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Ch-1PTPase antibody
    • Ch1 PTPase antibody
    • DKFZp781C1038 antibody
    • EC PTP antibody
    • ECPTP antibody
    • FLJ34328 antibody
    • MGC131968 antibody
    • MGC148170 antibody
    • NC PTPCOM1 antibody
    • NC-PTPCOM1 antibody
    • Protein tyrosine phosphatase Cr1PTPase precursor antibody
    • Protein tyrosine phosphatase NC PTPCOM1 antibody
    • Protein tyrosine phosphatase PCPTP1 antibody
    • Protein tyrosine phosphatase receptor type R antibody
    • Protein-tyrosine phosphatase PCPTP1 antibody
    • PTP SL antibody
    • PTPBR7 antibody
    • PTPRQ antibody
    • PTPRR antibody
    • PTPRR_HUMAN antibody
    • PTPSL antibody
    • R-PTP-R antibody
    • Receptor type tyrosine protein phosphatase R antibody
    • Receptor-type tyrosine-protein phosphatase R antibody
    see all

Images

  • All lanes : Anti-PCPTP1/PTPRQ antibody [EPR13188] (ab180134) at 1/5000 dilution

    Lane 1 : Human cerebellum lysate at 20 µg
    Lane 2 : Mouse brain lysate at 20 µg
    Lane 3 : Rat brain lysate at 10 µg

    Secondary
    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 74 kDa

References

ab180134 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab180134.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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