Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13188] to PCPTP1/PTPRQ
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Product nameAnti-PCPTP1/PTPRQ antibody [EPR13188]
See all PCPTP1/PTPRQ primary antibodies
DescriptionRabbit monoclonal [EPR13188] to PCPTP1/PTPRQ
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human PCPTP1/PTPRQ aa 1-100. The exact sequence is proprietary.
Database link: Q15256
- Human cerebellum, mouse and rat brain lysates.
This product was previously labelled as PCPTP1
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab180134 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Predicted molecular weight: 74 kDa.|
FunctionSequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
Tissue specificityExpressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
Contains 1 tyrosine-protein phosphatase domain.
Cellular localizationCell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
- Information by UniProt
- Ch-1PTPase antibody
- Ch1 PTPase antibody
- DKFZp781C1038 antibody
All lanes : Anti-PCPTP1/PTPRQ antibody [EPR13188] (ab180134) at 1/5000 dilution
Lane 1 : Human cerebellum lysate at 20 µg
Lane 2 : Mouse brain lysate at 20 µg
Lane 3 : Rat brain lysate at 10 µg
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 74 kDa
ab180134 has not yet been referenced specifically in any publications.