Overview

  • Product name
  • Description
    Rabbit polyclonal to PCSK2
  • Host species
    Rabbit
  • Specificity
    This antibody recognises the peptidase enzyme designated proprotein convertase 2 and also known as PC2, NEC2 and neuroendocrine convertase 2. This enzyme is involved in the processing of hormone (and other protein) precursors and is localised in secretory granules.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human, Monkey
  • Immunogen

    Recombinant full length protein corresponding to PCSK2.

  • General notes
    This product should be stored undiluted. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab11787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 70 kDa.

Target

  • Function
    Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.
  • Sequence similarities
    Belongs to the peptidase S8 family. Furin subfamily.
  • Cellular localization
    Cytoplasmic vesicle > secretory vesicle. Localized in the secretion granules.
  • Information by UniProt
  • Database links
  • Alternative names
    • KEX2 like endoprotease 2 antibody
    • KEX2-like endoprotease 2 antibody
    • NEC 2 antibody
    • NEC2 antibody
    • NEC2_HUMAN antibody
    • Neuroendocrine convertase 2 antibody
    • PC2 antibody
    • PCSK2 antibody
    • Prohormone convertase 2 antibody
    • Proprotein convertase 2 antibody
    • Proprotein convertase subtilisin/kexin type 2 antibody
    • SPC2 antibody
    see all

Images

  • Western blot using monkey brain extract and stained with ab11787 at 1:1000. The major band is running at ~62kDa.

References

ab11787 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

Thank you for your enquiry. Regarding ab3613 (HEC1 antibody [9G3]), the recommened positive control is HeLa whole cell lysate. HeLa related products can be found at: https://www.abcam.com/index.html?pageconfig=searchresults We also carry the immunizing HEC1 peptide (630-642)(ab22944) that was used to raise ab3613. This product can be used in blocking studies to address the question on specificity. At this time, we do not carry the human recombinant HEC1 protein. I hope this information helps. Please don't hesitate to contact us again if you have further questions.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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