Overview

  • Product name
  • Description
    Mouse polyclonal to PCSK7
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Chimpanzee
  • Immunogen

    Recombinant full length protein fragment, corresponding to amino acids 1-564 of Human DYX1C1 (AAH06357.1)

  • Positive control
    • Recombinant Human PCSK7 protein (ab132452) can be used as a positive control in WB. Lysate from 293T cells transfected with PCSK7.

Properties

Applications

Our Abpromise guarantee covers the use of ab168593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa.

Target

  • Function
    Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
  • Tissue specificity
    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
  • Sequence similarities
    Belongs to the peptidase S8 family.
    Contains 1 homo B/P domain.
  • Post-translational
    modifications
    Cysteine residues in the cytoplasmic tail are probably palmitoylated.
    N-glycosylated.
  • Cellular localization
    Golgi apparatus > trans-Golgi network membrane. Seems to be localized intracellularly to the trans Golgi network.
  • Information by UniProt
  • Database links
  • Alternative names
    • hPC8 antibody
    • LPC antibody
    • Lymphoma proprotein convertase antibody
    • PC7 antibody
    • PC8 antibody
    • Pcsk7 antibody
    • PCSK7_HUMAN antibody
    • Prohormone convertase 7 antibody
    • Prohormone convertase 8 antibody
    • Proprotein convertase 7 antibody
    • Proprotein convertase 8 antibody
    • Proprotein convertase PC7 antibody
    • Proprotein convertase subtilisin/kexin type 7 antibody
    • SPC7 antibody
    • Subtilisin/kexin-like protease PC7 antibody
    see all

Images

  • All lanes : Anti-PCSK7 antibody (ab168593) at 1 µg/ml

    Lane 1 : PCSK7-transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Developed using the ECL technique.

    Predicted band size: 64 kDa

References

ab168593 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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